Dr. Swapnil Pandey

About

My current research interest is the development and application of new technologies to define the molecular pathways leading to neurodegeneration and to identify potential therapeutic targets. To do so, we utilize the fruit fly Drosophila melanogaster to model molecular, biochemical and pathological aspects of human neurodegenerative conditions. This is achieved by disrupting homologous genes in Drosophila, or by expressing a human disease gene in this organism. Strikingly, the remarkable genetic conservation from flies to humans leads to neurological phenotypes that closely mimic the human disease. Once the model is validated, we apply a multidisciplinary approach combining Drosophila genetics, neurobiology, molecular biology, biochemistry, and systems biology.

Employment

• University of Florida Post Doctoral Associate
  2021 - Present
• CSIR-National Botanical Research Institute ICMR- Research Associate
  2020 - 2021
• CSIR-National Botanical Research Institute ICMR-SENIOR RESEARCH FELLOW
  2018 - 2020
• National Botanical Research Institute SENIOR PROJECT FELLOW
  2016 - 2017
• National Botanical Research Institute Project Assistant II
  2015 - 2016
• Central Institute of Medicinal and Aromatic Plants CSIR Project Assistant II
  2014 - 2015
• CSIR-Central Drug Research Institute PROJECT FELLOW
  2013 - 2014

Education

• Bundelkhand University M.Sc.
  2010 - 2012
• Bundelkhand University Bachelors of Science
  2007 - 2010

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• Identification of potential pathways and biomarkers linked to progression in ALS
  Annals of Clinical and Translational Neurology 2023 DOI: 10.1002/acn3.51697
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• Amelioration of Radiation-Induced Cell Death in Neuro2a Cells by Neutralizing Oxidative Stress and Reducing Mitochondrial Dysfunction Using N-Acetyl-L-Tryptophan.
  Oxidative medicine and cellular longevity 2022 DOI: 10.1155/2022/9124365
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• Hemiterpene compound, 3,3-dimethylallyl alcohol promotes longevity and neuroprotection in Caenorhabditis elegans
  GeroScience 2021 DOI: 10.1007/s11357-020-00241-w
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• Metagenomics Analysis of Thrombus Samples Retrieved from Mechanical Thrombectomy
  Neurointervention 2021 DOI: 10.5469/neuroint.2020.00353
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• Role of Phytomolecules on the Basic Biology of Aging
  Evidence Based Validation of Traditional Medicines 2021 DOI: 10.1007/978-981-15-8127-4_6
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• Betula utilis extract prolongs life expectancy, protects against amyloid-β toxicity and reduces Alpha Synuclien in Caenorhabditis elegans via DAF-16 and SKN-1
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2020 DOI: 10.1016/j.cbpc.2019.108647
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• Clinical Usefulness of Cell-Free DNA as a Prognostic Marker in Acute Ischemic Stroke
  The Neurologist 2020 DOI: 10.1097/nrl.0000000000000249
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• Essential Oils: Potential Application in Disease Management
  Antibacterial Drug Discovery to Combat MDR 2019 DOI: 10.1007/978-981-13-9871-1_14
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• Exploration of Soil Resistome Through a Metagenomic Approach
  Antibacterial Drug Discovery to Combat MDR 2019 DOI: 10.1007/978-981-13-9871-1_15
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• 3-Methyl-3-buten-1-ol (isoprenol) confers longevity and stress tolerance in Caenorhabditis elegans
  International Journal of Food Sciences and Nutrition 2019 DOI: 10.1080/09637486.2018.1554031
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