Jessica C. Orr

Employment

• University College, London Postdoctoral Research Fellow
  2024 - Present
• University College London Postdoctoral Researcher
  2023 - 2024
• University College London PhD Student
  2019 - 2023

Education

• Imperial College London Biological Sciences with a Year in Industry BSc (Hons)
  2015 - 2019

Projects & Funding

Projects & funding information is unavailable.

Publications (13)

• p63 regulates stem cell maintenance and age-associated functional decline in human airway basal cells
  2026 DOI: 10.64898/2026.07.22.740085
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• Podoplanin expression identifies human airway basal cells with higher progenitor cell potential
  2025 DOI: 10.64898/2025.12.17.694989
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• WS6 enables scalable ex vivo expansion and gene editing of human basal epithelial cells
  Jessica C. Orr, Elizabeth K. Haughey, Andrew S. Farr +26 more
  2025 DOI: 10.1101/2025.09.15.675861
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• Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
  Journal of Cell Science 2025 DOI: 10.1242/jcs.263487
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• A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence
  American Journal of Physiology-Lung Cellular and Molecular Physiology 2024 DOI: 10.1152/ajplung.00047.2024
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• Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
  2024 DOI: 10.1101/2024.08.13.606573
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• Lentiviral expression of wild-type LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa
  Molecular Therapy 2024 DOI: 10.1016/j.ymthe.2024.02.032
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• A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence
  2024 DOI: 10.1101/2024.02.09.579635
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• Lung viral infection modelling in a bioengineered whole-organ
  2023 DOI: 10.1101/2023.02.01.526441
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• Cell-intrinsic differences between human airway epithelial cells from children and adults
  Elizabeth F. Maughan, Robert E. Hynds, Adam Pennycuick

  +23 more

  • Ersilia Nigro
  • Kate H.C. Gowers
  • Céline Denais
  • Sandra Gómez‐López
  • Kyren A. Lazarus
  • +18 more
  iScience 2022 DOI: 10.1016/j.isci.2022.105409
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• Stem Cell–Derived Respiratory Epithelial Cell Cultures as Human Disease Models
  American Journal of Respiratory Cell and Molecular Biology 2021 DOI: 10.1165/rcmb.2020-0440TR
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• Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds
  European Respiratory Journal 2020 DOI: 10.1183/13993003.01200-2019
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• Cell-intrinsic differences between human airway epithelial cells from children and adults
  2020 DOI: 10.1101/2020.04.20.027144
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