Tintu Varghese

About

I am a physician-scientist specializing in enteric infections and vaccine research among children under five in low- and middle-income countries.
My research focuses on the etiology and burden of diarrheal diseases among children under five using molecular diagnostic tools, with a particular focus on the molecular epidemiology, immune responses, and vaccine responses to rotavirus and Shigella in India. I have evaluated the performance of indigenous rotavirus vaccines following their introduction into the national immunization program and examined the influence of breast milk components and the infant microbiome on vaccine response through longitudinal mother–infant cohort studies. I also contribute to WHO-supported pediatric diarrheal surveillance initiatives and serve as laboratory lead for rotavirus reference activities in the WHO SEARO region, integrating field epidemiology and molecular diagnostics to inform immunization policy and child health programs.

Employment

• Christian Medical College & Hospital Associate Professor
  2025 - Present
• Christian Medical College, Vellore Assistant Professor
  2020 - 2025
• Christian Medical College & Hospital Medical Research Fellow
  2019 - 2020
• KMCT Medical College Assistant Professor
  2018 - 2019
• Government Medical College Thrissur Senior Resident
  2017 - 2018

Education

• Tamil Nadu Dr. M.G.R. Medical University Doctor of Philosophy
  2021 - 2025
• Madras Medical College MBBS
  2007 - 2012
• Royal College of Physicians Diploma in Tropical Medicine and Hygiene

Projects & Funding

Projects & funding information is unavailable.

Publications (44)

• Genotype Distribution of Rotavirus Strains and Its Association with Severity of Diarrhea Among Children Under Five Hospitalized with Acute Gastroenteritis in Odisha, India: Authors’ Reply
  Indian Journal of Pediatrics 2026 DOI: 10.1007/s12098-026-06138-4
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• Universal immunization program in India: a review of childhood vaccine updates over the last decade (2014-2024)
  IJID Regions 2026 DOI: 10.1016/j.ijregi.2026.100957
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• Fecal Calprotectin as a biomarker for early diagnosis and prediction of steroid response in Acute Gastrointestinal Graft versus Host Disease.
  Blood cell therapy 2026 DOI: 10.31547/bct-2025-016
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• Molecular epidemiology of rotavirus causing diarrhea among under-five children after the introduction of rotavirus vaccines, Rotavac and Rotasiil, into the national immunization program of India.
  Virology journal 2026 DOI: 10.1186/s12985-026-03126-0
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• The Global Pediatric Diarrhea Surveillance network: Rationale and methods
  2026 DOI: 10.64898/2026.05.21.26352576
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• Establishment of an External Quality Assessment Scheme for Clinical Parasitology Diagnostics in India: Four years of experience (2022-2025)
  2026 DOI: 10.64898/2026.07.22.26358636
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• Etiology and incidence of diarrhea requiring hospitalization in children under 5 years of age in 31 low- and middle-income countries: findings from the Global Pediatric Diarrhea Surveillance network, 2017–2022
  2026 DOI: 10.64898/2026.07.26.26358975
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• Performance of Oral Rotavirus Vaccines in Low- and Middle-Income Settings: Current Evidence, Persistent Gaps and Future Directions
  Viruses 2026 DOI: 10.3390/v18080917
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• Global trends in norovirus genotype distribution among medically attended children with acute gastroenteritis, 2020–2025
  Journal of Clinical Virology 2026 DOI: 10.1016/j.jcv.2026.105949
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• Genotype Distribution of Rotavirus Strains and Its Association with Severity of Diarrhea Among Children Under Five Hospitalized with Acute Gastroenteritis in Odisha, India.
  Indian journal of pediatrics 2025 DOI: 10.1007/s12098-025-05773-7
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