JB
John Kenneth Baillie
University of Edinburgh Roslin Institute
Research areas: Medicine · Infectious Diseases · COVID-19 Clinical Research Studies · SARS-CoV-2 and COVID-19 Research · Genomics and Chromatin Dynamics
Employment
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University of Edinburgh Roslin Institute2009 - Present
Education
Education history is unavailable.
Projects & Funding
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The Edinburgh Molecular Mechanisms Cluster Medical Research Council2024 - 2028
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Causality in Healthcare AI Hub Engineering and Physical Sciences Research Council2024 - 2029
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Genes & Traits for Healthy Animals: Identifying the genomic basis of complex traits in farmed animals Biotechnology and Biological Sciences Research Council2023 - 2028
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Genes & Traits for Healthy Animals: Defining genome activity Biotechnology and Biological Sciences Research Council2023 - 2028
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Prevention & Control of Infectious Diseases: Understanding the basis of host resistance Biotechnology and Biological Sciences Research Council2023 - 2028
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Genes & Traits for Healthy Animals: Understanding the origins of animal phenotypes Biotechnology and Biological Sciences Research Council2023 - 2028
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Interim support for ISARIC4C Clinical Characterisation Protocol (CCP) activation for acute severe hepatitis in children of unknown cause Medical Research Council2022 - 2023
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ISARIC CCP activation for acute hepatitis of unknown cause Medical Research Council2022 - 2024
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HElping Alleviate the Longer-term consequences of COVID-19 (HEAL-COVID): A national platform trial National Institute for Health and Care Research2021 - 2025
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Human ACE2 transgenic pigs: A large animal model for Covid-19 Biotechnology and Biological Sciences Research Council2021 - 2022
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The UK Interstitial Lung Disease Long-COVID19 study (UKILD-Long COVID): understanding the burden of Interstitial Lung Disease in Long COVID. Medical Research Council2021 - 2023
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Investigation of proven vaccine breakthrough by SARS-CoV-2 variants in established UK healthcare worker cohorts: SIREN consortium & PITCH Plus Pathway Medical Research Council2021 - 2023
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Translational genomics in critical care medicine. Wellcome2021 - 2026
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ISARIC - Coronavirus Clinical Characterisation Consortium (ISARIC-4C) Medical Research Council2020 - 2022
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COVID-19 GenOMICC-GENOMICS ENGLAND PARTNERSHIP Medical Research Council2020 - 2021
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PHOSP-COVID Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes Medical Research Council2020 - 2022
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CO-CONNECT: COVID - Curated and Open aNalysis aNd rEsearCh plaTform Medical Research Council2020 - 2022
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COVID-19: Improving the Evidence to Treat an Emerging Infection Through Observational Studies and a Randomized Trial Canadian Institutes of Health Research2020 - 2022
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COVID-19: Improving the Evidence to Treat an Emerging Infection Through Observational Studies and a Randomized Trial Canadian Institutes of Health Research2020 - 2022
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The African coaLition for Epidemic Research, Response and Training, Clinical Characterization Protocol (ALERRT CCP) Wellcome Trust2020 - 2022
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A UK underpinning platform to study immunology and immunopathology of COVID-19:The UK Coronavirus Immunology Consortium Medical Research Council2020 - 2022
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ISARIC - Coronavirus Clinical Characterisation Consortium (ISARIC-4C) Medical Research Council2020 - 2020
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Combining genetic and functional genomic data to reveal underlying mechanisms of human disease Medical Research Council2019 - 2023
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Host factors controlling foot-and-mouth disease virus (FMDV) replication: towards genetic control of FMD in pigs Biotechnology and Biological Sciences Research Council2019 - 2023
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Identification of interferon stimulated genes that restrict cross-species transmission of influenza A virus. Biotechnology and Biological Sciences Research Council2019 - 2023
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Large memory HPC infrastructure to underpin world-class biological research Biotechnology and Biological Sciences Research Council2019 - 2020
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Induction of tolerance to influenza virus by targeting the p38 MAP kinase signalling pathway Wellcome Trust2018 - 2020
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The function of genes and cellular phenotypes in animal systems Biotechnology and Biological Sciences Research Council2017 - 2020
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Generation of genome-wide CRISPR knockout libraries for pig and chicken Biotechnology and Biological Sciences Research Council2016 - 2017
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Identification of therapeutically-relevant patient subgroups from clinical and biological data Medical Research Council2016 - 2020
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Optimising Innate Host Defence to Combat Antimicrobial Resistance Medical Research Council2016 - 2022
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Identification and characterisation of host factors underlying susceptibility to influenza. Wellcome Trust2014 - 2020
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Identification and characterisation of host factors underlying susceptibility to influenza. Wellcome Trust2014 - 2020
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Mechanisms of severe acute influenza consortium (MOSAIC). Wellcome Trust2011 - 2014
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Wellcome Trust PhD Programme for Clinicians at the University of Edinburgh: 'Comparative genomics of the inflammatory response'. Wellcome Trust2009 - 2012
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GenISIS: Genetics of Influenza Susceptibility in Scotland: a parallel study to mecjhanisms of severe influenza consortium (MOSAIC) Chief Scientist Office2009 - 2010
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Mechanisms of severe acute influenza consortium (MOSAIC). Wellcome Trust2009 - 2012
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Understanding behaviour and spread of COVID-19 in the UK National Institute for Health Research
Publications (289)
- Integrated genomic meta-analysis identifies cell-type-specific signatures and targets in early Alzheimer’s disease Save
- Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages Save
- Identification of key host genes for influenza A virus in avian cells using a genome-wide CRISPR-Cas9 screen Save
- Genome-Scale Meta-analysis of Host Responses to Staphylococcus aureus Identifies Pathways for Host-Directed Therapeutic Targeting Save
- Building an international precision medicine platform trial for the acute respiratory distress syndrome (ARDS): an expert consensus project report Save
- Direct Retinal Imaging for Shock Resuscitation in Critical Ill Adults II (D-RISC II) Save
- Diagnostic Accuracy of 3 Mpox Lateral Flow Assays for Antigen Detection, Democratic Republic of the Congo and United Kingdom Save
- Evaluation of the diagnostic accuracy of Xpert® Mpox and STANDARDTM M10 MPX/OPX for the detection of monkeypox virus Save
- Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity Save
- IL-33 is associated with alveolar dysfunction in patients with viral lower respiratory tract disease Save
- What can be learned about acute respiratory distress syndrome from severe COVID-19: a comparison of meta-analyses by information content Save
- Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis Save
- Dual site proteomic analyses reveal potential drug targets for cardiovascular disease Save
- A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies Save
- Accelarated immune ageing is associated with COVID-19 disease severity Save
- Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19 Save
- Development and external validation of the 'Global Surgical-Site Infection' (GloSSI) predictive model in adult patients undergoing gastrointestinal surgery Save
- Diagnostic accuracy of three mpox lateral flow assays for antigen detection in the Democratic Republic of Congo and the United Kingdom Save
- Evaluation of the diagnostic accuracy and analytical sensitivity of the novel Xpert® Mpox (Cepheid®) and STANDARD™ M10 MPX/OPX (SD Biosensor) molecular point-of-care assays for the detection of Mpox virus in skin lesion swabs and upper-respiratory swab s… Save
- Identifying cell-type specific AAV vectors for precision lung gene editing Save