Shradha Suyal

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Publications (9)

• Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast
  Biochemical Journal 2024 DOI: 10.1042/BCJ20240447
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• Identification of Juglone, a ‘first-in-class’ inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast-based high throughput screens
  2024 DOI: 10.1101/2024.07.21.604522
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• ChaC1 upregulation reflects poor prognosis in a variety of cancers: analysis of the major missense SNPs of ChaC1 as an aid to refining prognosis
  Gene 2024 DOI: 10.1016/j.gene.2024.148386
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• The ChaC1 active site: Defining the residues and determining the role of ChaC1‐exclusive residues in the structural and functional stability
  Proteins: Structure, Function, and Bioinformatics 2023 DOI: 10.1002/prot.26450
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• Investigation of BRCA1 methylation and FAT3 mutation as a potential biomarker in ovarian cancer samples
  Human Gene 2022 DOI: 10.1016/j.humgen.2022.201032
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• Cysteine–phenylalanine-derived self-assembled nanoparticles as glutathione-responsive drug-delivery systems in yeast
  Journal of Materials Chemistry B 2022 DOI: 10.1039/d2tb01362b
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• Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism.
  The Journal of biological chemistry 2020 DOI: 10.1074/jbc.ra120.015129
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• In silico screening of proteins targeting circulating miRNAs for improved diagnosis of multiple myeloma
  Biochemical and Biophysical Research Communications 2018 DOI: 10.1016/j.bbrc.2018.02.103
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• Genetic and epigenetic markers in colorectal cancer screening: recent advances
  Expert Review of Molecular Diagnostics 2017 DOI: 10.1080/14737159.2017.1337511
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