JK

Joseph Keane

Trinity College Dublin, Trinity College Dublin Faculty of Health Sciences, University College Dublin, Saint James's Hospital

ORCID iD 0000-0001-5313-385X
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About

I am the Professor of Medicine and Head of Department of Clinical Medicine at Trinity College Dublin, a Consultant Respiratory Physician in St. James’s Hospital and twice holder of the Health Research Board Clinician Scientist Award. I co-direct the Tuberculosis Service at our national centre at St. James’ Hospital. I am on the advisory group that leads on TB control policy nationally and internationally; towards eradication of this infectious disease that has massive negative societal impact.
Research interests include: Tuberculosis and TB Diagnostics, Infectious diseases, Innate immunology, Molecular and Translational Medicine, Lung diseases, Lung Cancer, Apoptosis, Host Pathogen interactions, Global and Population Health.
Example of Research projects:
• Defining the tuberculosis susceptibility of smokers
• Improving TB vaccines by dendritic cell manipulation
• Developing inhalable microparticles as adjuvant therapy for tuberculosis
• Improving the host response to tuberculosis with retinoids
• Defining the immunometabolomics of TB host response
• Characterising the contribution of Mal to the Interferon gamma driven host response to Mtb.
Research sponsors include; the Health Research Board, Science Foundation Ireland and Royal City of Dublin Hospital Trust. Research output: 132 publications and 11,500 citations, including the journal article on ‘TB and TNF’ cited more than 4800 times. (Source Google scholar)
Impact of Published Research
Research: Definitive report of TB associated with biologics treatment -> Impact: Biologic therapy now safer-> Citation: New England Journal of Medicine 2001

Employment

  • Trinity College Dublin Head of Department of Clinical Medicine
    2018 - Present
  • Trinity College Dublin Professor of Medicine (1922)
    2018 - Present
  • Trinity College Dublin Faculty of Health Sciences Professor Of Medicine
    2012 - Present
  • Trinity College Dublin Faculty of Health Sciences Head of Department (Interim)
    2012 - 2014
  • University of Dublin Trinity College Associate Professor Of Medicine
    2008 - 2012
  • Trinity College Dublin Faculty of Health Sciences Director of Research
    2006 - 2008
  • Trinity College Dublin Director of Research, School of Medicine,
    2006 - 2008
  • University of Dublin Trinity College Senior Lecturer in Clinical Medicine
    2004 - 2008
  • Saint James's Hospital Consultant Respiratory Physician
    2002 - Present
  • Boston University Medical Campus Assistant Professor of Medicine
    1996 - 2002
  • Boston University School of Medicine Respiratory, Critical Care and Research Fellowship
    1993 - 1996
  • University College Dublin College of Health Sciences Lecturer in Pharmacology
    1992 - 1993
  • Saint Vincent's Hospital Dublin Respiratory Registrar
    1991 - 1992
  • Federated Dublin Hospitals SHO rotation (Internal Medicine)
    1989 - 1999
  • Saint James's Hospital Intern Year
    1988 - 1989

Education

  • Trinity College Dublin Doctorate of Medicine
    ? - 1999
  • University College Dublin BSc. in Pharmacology
    ? - 1993
  • Trinity College Dublin Faculty of Health Sciences Honours MB. BAO BCh BA
    ? - 1988

Projects & Funding

Projects & funding information is unavailable.

Publications (141)