MA
Madhavi Annamanedi
National Institute of Animal Biotechnology, West Virginia University, University of Hyderabad
Research areas: Medicine · Pediatrics, Perinatology and Child Health · Neonatal and Maternal Infections · Antimicrobial Resistance in Staphylococcus · Sepsis Diagnosis and Treatment
0000-0001-5460-6532
About
I am a researcher working on alternate antibacterial therapies. Graduate study focused on repurposing an anti-inflammatory drug to improve the efficacy of an antibiotic in treating resistant bacterial infections. Also done molecular epidemiology of bovine mastitis S aureus in India. Now, exploring the IL-27 cytokine, therapeutic intervention during neonatal sepsis.
Employment
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National Institute of Animal Biotechnology Postdoctoral researcher
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West Virginia University Postdoctoral researcher
Education
- 2012 - 2017
Projects & Funding
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A combinatorial approach to reduce antibiotic use against biofilm forming, major staphylococci associated with bovine and bubaline mastitis DBT
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STUDY THE PREVALENCE OF MEC (MECA/MECC) POSITIVE STAPHYLOCOCCUS AUREUS IN HUMAN POPULATION OF HYDERABAD AND STUDY OF COMBINATORIAL EFFICACY OF CELECOXIB AND ANTIBIOTIC ON MRSA SUBCUTANEOUS INFECTION MOUSE MODEL AND CLINICAL ISOLATED MRSA STRAINS ICMR
Publications (17)
- Inhibition of IL-27 signaling regulates chemokine levels and sustains CXCR2 receptor expression on mononuclear cells to improve disease outcomes during gram-negative neonatal sepsis. Save
- Interleukin-27-producing cells in gram-negative neonatal sepsis display diverse phenotypes and functions in the liver. Save
- STAT-3 is necessary for IL-27-mediated macrophage suppression but does not represent a therapeutic target for E. coli -induced neonatal sepsis Save
- The influence of interleukin-27 on metabolic fitness in a murine neonatal model of bacterial sepsis. Save
- Genome sequencing and comparative genomic analysis of bovine mastitis-associated non-aureus staphylococci and mammaliicocci (NASM) strains from India Save
- Genome sequencing and comparative genomic analysis of bovine mastitis-associated non-aureus staphylococci and mammaliicocci (NASM) strains from India Save
- Neonatal Mouse Bone Marrow Isolation and Preparation of Bone Marrow-Derived Macrophages Save
- Interleukin-27-dependent transcriptome signatures during neonatal sepsis Save
- Genome sequencing and comparative genomic analysis of bovine mastitis-associated Staphylococcus aureus strains from India Save
- Molecular fingerprinting of bovine mastitis-associated Staphylococcus aureus isolates from India. Save
- Molecular Characterisation of Methicillin-Resistant Staphylococcus aureus Isolated from Patients at a Tertiary Care Hospital in Hyderabad, South India Save
- Impact of antimicrobial use in animals on antimicrobial resistance in humans Save
- Impact of Polymorphisms in Casein Kinase 1 Epsilon and Environmental Factors in Oral Cancer Susceptibility Save
- Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens Save
- Celecoxib Sensitizes Staphylococcus aureus to Antibiotics in Macrophages by Modulating SIRT1 Save
- Synthesis of mesoporous SiO2–ZnO nanocapsules: encapsulation of small biomolecules for drugs and “SiOZO-plex” for gene delivery Save
- Synthesis of mesoporous SiO2-ZnO nanocapsules: Encapsulation of small biomolecules for drugs and "SiOZO-plex" for gene delivery Save