James Cotton
University of Glasgow, Wellcome Sanger Institute
Research areas: Medicine · Public Health, Environmental and Occupational Health · Research on Leishmaniasis Studies · Genomics and Phylogenetic Studies · Trypanosoma species research and implications
0000-0001-5475-3583
About
I am a professor in the Institute of Biodiversity, One Health and Comparative Medicine at the University of Glasgow.
I studied biology at Oxford, and then did a PhD on gene family evolution with Rod Page at the University of Glasgow, followed by post-docs at the Natural History Museum in London and at the National University of Ireland, Maynooth, working on various topics in phylogenetics and molecular evolution. I was subsequently an RCUK Fellow at Queen Mary, University of London for three years before joining the parasite genomics group at the Sanger Institute in 2010 as a senior staff scientist, where I stayed until joining the University of Glasgow in 2022.
I'm worked on a diverse array of parasitic species, including nematodes, schistosomes and kinetoplastids. I played a leading role in a number of de-novo genome sequencing projects, but particularly focus on projects with a strong comparative or population genomics component.
Employment
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University of Glasgow Professor2022 - Present
- ? - 2022
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (148)
- Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis , a primary agent of mucocutaneous leishmaniasis Save
- Different isolates of Leishmania aethiopica elicit distinct effector functions in primary human monocytes Save
- Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica Save
- Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica Save
- Evolutionary genomics of Leishmania braziliensis across the neotropical realm. Save
- Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica. Save
- Demographic characteristics and clinical features of patients presenting with different forms of cutaneous leishmaniasis, in Lay Gayint, Northern Ethiopia. Save
- Extensive transmission and variation in a functional receptor for praziquantel resistance in endemicSchistosoma mansoni Save
- A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture Save
- Demographic characteristics and prevalence of asymptomatic Leishmania donovani infection in migrant workers working in an endemic area in Northwest Ethiopia. Save
- Diversity and dissemination of viruses in pathogenic protozoa. Save
- Genomic Heterogeneity of Cryptosporidium parvum Isolates From Children in Bangladesh: Implications for Parasite Biology and Human Infection. Save
- Cutaneous leishmaniasis in a newly established treatment centre in the Lay Gayint district, Northwest Ethiopia Save
- Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics Save
- Recurrent visceral leishmaniasis relapses in HIV co-infected patients are characterized by less efficient immune responses and higher parasite load Save
- A genetic TRP down the channel to praziquantel resistance Save
- Systematic identification of genes encoding cell surface and secreted proteins that are essential for in vitro growth and infection in Leishmania donovani Save
- Development and validation of a quantitative PCR for the detection of Guinea worm (Dracunculus medinensis) Save
- Following successful anti-leishmanial treatment, neutrophil counts, CD10 expression and phagocytic capacity remain reduced in visceral leishmaniasis patients co-infected with HIV Save
- Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities Save