PAVAN KUMAR SAMUDRALA

About

Our current research mainly focuses on the evaluation of pharmacological potencies of various herbal products, Phyto pharmaceutical drugs, NCE’s against various in vivo diseases models, particularly depression, neurodegenerative diseases like Parkinson’s disease, and cognitive impairment. We are studying the various pathophysiological cascades of these diseases, which include oxidative stress, ER stress, inflammation and Apoptosis.

Employment

• Shri Vishnu College of Pharmacy Associate Professor
  2021 - Present
• National Institute of Pharmaceutical Education and Research Guwahati Assistant Professor
  2015 - 2020
• Annamacharya College of Pharmacy Assistant Professor
  2014 - 2015

Education

• National Institute of Pharmaceutical Education and Research Guwahati Ph.D
  2011 - 2015
• National Institute of Pharmaceutical Education and Research Guwahati M.S.(Pharm.)
  2009 - 2011
• Chalapathi Institute of Pharmaceutical Science B.Pharmacy
  2005 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (28)

• Therapeutic Potential of Stearylamine-Conjugated Phenylboronic Acid-Modified Nanocarriers of 4-Allyl Pyrocatechol in Modulating Sialylation and Neuroinflammation in Scopolamine-Induced Cognitive Impairment in the Rat Model
  Molecular Pharmaceutics 2026 DOI: 10.1021/acs.molpharmaceut.5c01768
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• “Clinical and radiological evaluation of periodontal intrabony defects treated with DFDBA and 1% melatonin gel and its effect on RANKL and OPG in gingival crevicularfluid – a randomized controlled trial”
  Clinical Oral Investigations 2025 DOI: 10.1007/s00784-025-06624-7
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• Saroglitazar, a PPAR α/γ agonist alleviates 3-Nitropropionic acid induced neurotoxicity in rats: Unveiling the underlying mechanisms
  NeuroToxicology 2024 DOI: 10.1016/j.neuro.2024.09.004
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• Ameliorative effect of ferulic acid on thyroid dysfunction against propyl-thiouracil induced hypothyroid rats
  Endocrine 2024 DOI: 10.1007/s12020-024-03818-z
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• Omentum Extracellular Matrix-Silk Fibroin Hydroscaffold Promotes Wound Healing through Vascularization and Tissue Remodeling in the Diabetic Rat Model
  ACS Biomaterials Science & Engineering 2024 DOI: 10.1021/acsbiomaterials.3c01877
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• Montelukast Ameliorates Scopolamine-induced Alzheimer’s Disease: Role on Cholinergic Neurotransmission, Antioxidant Defence System, Neuroinflammation and Expression of BDNF
  CNS & Neurological Disorders - Drug Targets 2023 DOI: 10.2174/0118715273258337230925040049
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• Neuroprotective Effect of Saroglitazar on Scopolamine-Induced Alzheimer’s in Rats: Insights into the Underlying Mechanisms
  ACS Chemical Neuroscience 2023 DOI: 10.1021/acschemneuro.3c00320
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• Advancing health care via artificial intelligence: From concept to clinic
  European Journal of Pharmacology 2022 DOI: 10.1016/J.EJPHAR.2022.175320
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• UHPLC-DAD Method Development and Validation: Degradation Kinetic, Stress Studies of Farnesol and Characterization of Degradation Products Using LC-QTOF-ESI-MS with in silico Pharmacokinetics and Toxicity Predictions
  Journal of Chromatographic Science 2022 DOI: 10.1093/CHROMSCI/BMAB127
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• An updated review on potential therapeutic drug candidates, vaccines and an insight on patents filed for COVID-19
  Current Research in Pharmacology and Drug Discovery 2021 DOI: 10.1016/J.CRPHAR.2021.100063
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