YX
Yue Xu
Shanghai Jiao Tong University School of Medicine, National Institute of Biological Sciences, Beijing, China Agricultural University
Research areas: Biochemistry, Genetics and Molecular Biology · Structural Biology · Escherichia coli research studies · Enzyme Structure and Function · Genetic diversity and population structure
0000-0001-5524-1977
Employment
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Shanghai Jiao Tong University School of Medicine Principal Investigator2021 - Present
- 2019 - 2021
Education
- 2012 - 2019
- 2008 - 2012
Projects & Funding
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Study on the role of V-ATPase-ATG16L1 mediated selective autophagy in the repair of endomembrane damage National Natural Science Foundation of China2022 - 2025
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Interaction of bacterial infection and host defense China Association for Science and Technology
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A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy WuXi AppTec
Publications (14)
- Bacterial effector OspB hijacks apoptosis through peptide-bond recombination of BH3 domain proteins. Save
- Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis Save
- Configuration-Specific Antibody for Bacterial Heptosylation: An Antiadhesion Therapeutic Strategy Save
- Endomembrane damage sensing by V-ATPase recruits ATG16L1 for LC3 lipidation in situ Save
- Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases Save
- ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy Save
- Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11 Save
- The Yersinia Type III Secretion System as a Tool for Studying Cytosolic Innate Immune Surveillance Save
- A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy Save
- Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose Save
- N ε-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function Save
- A polar-localized iron-binding protein determines the polar targeting of Burkholderia BimA autotransporter and actin tail formation Save
- A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family Save
- An iron-containing dodecameric heptosyltransferase family modifies bacterial autotransporters in pathogenesis Save