Perunthottathu K. Umasankar

Employment

• Rajiv Gandhi Centre for Biotechnology Scientist & DBT- Ramalingaswami Faculty Fellow
  2016 - Present

Education

• National Centre for Cell Science, Savitribai Phule Pune University Ph.D.

Projects & Funding

Projects & funding information is unavailable.

Publications (15)

• Cholesterol regulates insulin-induced mTORC1 signaling
  Journal of Cell Science 2023 DOI: 10.1242/jcs.261402
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• FCHO controls AP2’s initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch
  Science Advances 2022 DOI: 10.1126/sciadv.abn2018
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• FCHO controls AP2’s critical endocytic roles through a PtdIns4,5P2 membrane-dependent switch
  2022 DOI: 10.1101/2022.04.02.486817
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• BMP2K phosphorylates AP‐2 and regulates clathrin‐mediated endocytosis
  Traffic 2021 DOI: 10.1111/tra.12814
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• Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction
  2020 DOI: 10.1101/2020.05.02.071811
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• Allosteric feed-forward activation of AP-2 via FCHO-BMP2K axis promotes clathrin-mediated endocytosis
  [] 2019 DOI: 10.1101/870899
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• Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding
  Developmental Cell 2015 DOI: 10.1016/j.devcel.2016.05.003
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• A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing
  eLife 2014 DOI: 10.7554/eLife.04137
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• A phosphotyrosine switch for cargo sequestration at clathrin-coated buds
  Journal of Biological Chemistry 2014 DOI: 10.1074/jbc.M114.556589
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• Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning
  Nature Cell Biology 2012 DOI: 10.1038/ncb2473
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