Nilesh Aghera

Employment

• Indian Institute of Science INSPIRE Faculty
  2014 - Present
• Indian Institute of Science DS Kothari Postdoctoral Fellow
  2014 - 2014
• National Centre for Biological Sciences Postdoctoral Fellow
  2013 - 2014

Education

• National Centre for Biological Sciences PhD
  2006 - 2013

Projects & Funding

Projects & funding information is unavailable.

Publications (9)

• CcdB at pH 4 Forms a Partially Unfolded State with a Dry Core
  Chetana Baliga, Benjamin Selmke, Irina Worobiew

  +5 more

  • Peter P. Borbat
  • Siddhartha P. Sarma
  • Wolfgang E. Trommer
  • Raghavan Varadarajan
  • Nilesh K. Aghera
  Biophysical Journal 2019 DOI: 10.1016/j.bpj.2019.01.026
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• Stepwise Assembly of β-Sheet Structure during the Folding of an SH3 Domain Revealed by a Pulsed Hydrogen Exchange Mass Spectrometry Study
  Nilesh K. Aghera, Jayant B. Udgaonkar
  Biochemistry 2017 DOI: 10.1021/acs.biochem.7b00374
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• Homodimeric Escherichia coli Toxin CcdB (Controller of Cell Division or Death B Protein) Folds via Parallel Pathways
  Chetana Baliga, Raghavan Varadarajan, Nilesh K. Aghera
  Biochemistry 2016 DOI: 10.1021/acs.biochem.6b00726
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• Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis Data
  Arti Tripathi, Kritika Gupta, Shruti Khare

  +6 more

  • Pankaj C. Jain
  • Siddharth Patel
  • Prasanth Kumar
  • Ajai J. Pulianmackal
  • Nilesh K. Aghera
  • +1 more
  Molecular Biology and Evolution 2016 DOI: 10.1093/molbev/msw182
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• The utilization of competing unfolding pathways of monellin is dictated by enthalpic barriers
  Nilesh K. Aghera, Jayant B. Udgaonkar
  Biochemistry 2013 DOI: 10.1021/bi400688w
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• A buried ionizable residue destabilizes the native state and the transition state in the folding of monellin
  Nilesh K. Aghera, Ishita Dasgupta, Jayant B. Udgaonkar
  Biochemistry 2012 DOI: 10.1021/bi3008017
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• Kinetic studies of the folding of heterodimeric monellin: Evidence for switching between alternative parallel pathways
  Nilesh K. Aghera, Jayant B. Udgaonkar
  Journal of Molecular Biology 2012 DOI: 10.1016/j.jmb.2012.04.019
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• Equilibrium unfolding studies of monellin: The double-chain variant appears to be more stable than the single-chain variant
  Nilesh K. Aghera, Ninganna Earanna, Jayant B. Udgaonkar
  Biochemistry 2011 DOI: 10.1021/bi101955f
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• Heterologous expression, purification and characterization of heterodimeric monellin
  Nilesh K. Aghera, Jayant B. Udgaonkar
  Protein Expression and Purification 2011 DOI: 10.1016/j.pep.2010.11.002
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