Stuart SEALFON

Employment

Employment history is unavailable.

Education

• Columbia University College of Physicians and Surgeons M.D.
  1978 - 1982
• Princeton University A.B.
  1974 - 1978

Projects & Funding

• PAGES: Physical Activity Genomics, Epigenomics/transcriptomics Site National Institute of Diabetes and Digestive and Kidney Diseases
  2016 - 2022
• Separating Wheat from Chaff in Major Depression Blood Biomarker Studies National Institute of Mental Health
  2016 - 2018
• Modeling Early Immunity to Human Influenza Infection National Institute of Allergy and Infectious Diseases
  2015 - 2020
• Mount Sinai Neurology Resident-Researcher Training Program National Institute of Neurological Disorders and Stroke
  2012 - 2017
• Mount Sinai Neurology Resident - Researcher Training Program National Institute of Neurological Disorders and Stroke
  2012 - 2022
• Modeling Immunity for Biodefense: Influenza virus National Institute of Allergy and Infectious Diseases
  2010 - 2015
• Modeling Immunity for Biodefense National Institute of Allergy and Infectious Diseases
  2005 - 2010
• Hallucinogens and 5-HT Receptors: Mechanisms and Effects National Institute on Drug Abuse
  2000 - 2013
• Molecular Mechanisms of Dopamine Receptor Mediated Neuroprotection Congressionally Directed Medical Research Programs
  1997 - 1998
• EVOLUTION OF THE GNRH RECEPTOR AND ITS BINDING Fogarty International Center
  1996 - 2000
• EVOLUTION OF THE GNRH RECEPTOR AND ITS BINDING Fogarty International Center
  1996 - 2000
• RECEPTOR DETERMINANTS OF HALLUCINOGEN ACTIONS National Institute on Drug Abuse
  1994 - 2001
• RECEPTOR DETERMINANTS OF HALLUCINOGEN ACTIONS National Institute on Drug Abuse
  1994 - 2001
• GnRH Receptor Signaling Specificity National Institute of Diabetes and Digestive and Kidney Diseases
  1993 - 2017
• GnRH Receptor Signaling Specificity National Institute of Diabetes and Digestive and Kidney Diseases
  1993 - 2017
• GnRH Receptor Signaling Specificity National Institute of Diabetes and Digestive and Kidney Diseases
  1993 - 2018
• GnRH Receptor Signaling Specificity National Institute of Diabetes and Digestive and Kidney Diseases
  1993 - 2008
• Molecular Biology and Biosynthetic Regulation of the GnRH Receptor National Science Foundation
  1991 - 1994
• REGULATION OF NEURO-HORMONE RECEPTORS National Institute of Diabetes and Digestive and Kidney Diseases
  1988 - 1993
• REGULATION OF NEURO-HORMONE RECEPTORS National Institute of Diabetes and Digestive and Kidney Diseases
  1988 - 1993
• Interdisciplinary Training in Drug Abuse Research National Institute on Drug Abuse
  1979 - 2019

Publications (192)

• Automated single-cell omics end-to-end framework with data-driven batch inference
  2023 DOI: 10.1101/2023.11.01.564815
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• Peak-agnostic high-resolution cis-regulatory circuitry mapping using single cell multiome data
  2023 DOI: 10.1101/2023.06.23.544355
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• Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination
  npj Vaccines 2022 DOI: 10.1038/s41541-022-00583-w
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• Earlier detection of SARS‐CoV‐2 infection by blood RNA signature microfluidics assay
  Clinical and Translational Discovery 2022 DOI: 10.1002/ctd2.47
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• Optimization of the Omni-ATAC protocol to chromatin accessibility profiling in snap-frozen rat adipose and muscle tissues
  MethodsX 2022 DOI: 10.1016/j.mex.2022.101681
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• Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19
  The Journal of Immunology 2021 DOI: 10.4049/jimmunol.2100135
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• Pathway-level information extractor (PLIER) for gene expression data
  Nature Methods 2019 DOI: 10.1038/s41592-019-0456-1
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• Interpretation of an individual functional genomics experiment guided by massive public data
  Nature Methods 2018 DOI: 10.1038/s41592-018-0218-5
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• Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation
  Blood Advances 2018 DOI: 10.1182/bloodadvances.2018024273
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• High resolution annotation of zebrafish transcriptome using long-read sequencing
  Genome Research 2018 DOI: 10.1101/gr.223586.117
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• Regulatory architecture of the LβT2 gonadotrope cell underlying the response to gonadotropin-releasing hormone
  Frontiers in Endocrinology 2018 DOI: 10.3389/fendo.2018.00034
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• Single-cell stabilization method identifies gonadotrope transcriptional dynamics and pituitary cell type heterogeneity
  Nucleic Acids Research 2018 DOI: 10.1093/nar/gky991
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• Tellurium notebooks—An environment for reproducible dynamical modeling in systems biology
  PLoS Computational Biology 2018 DOI: 10.1371/journal.pcbi.1006220
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• Tellurium Notebooks - An Environment for Dynamical Model Development, Reproducibility, and Reuse
  2017 DOI: 10.1101/239004
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• Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency
  Journal of Biological Chemistry 2017 DOI: 10.1074/jbc.M117.783886
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• Elucidation of molecular kinetic schemes from macroscopic traces using system identification
  PLoS Computational Biology 2017 DOI: 10.1371/journal.pcbi.1005376
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• Multiscale Modeling of Complex Formation and CD80 Depletion during Immune Synapse Development
  Biophysical Journal 2017 DOI: 10.1016/j.bpj.2016.12.052
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• Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death
  Nature Communications 2017 DOI: 10.1038/s41467-017-02035-9
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• Solving Immunology?
  Trends in Immunology 2017 DOI: 10.1016/j.it.2016.11.006
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• Characterization of gonadotrope secretoproteome identifies neurosecretory protein VGF-derived peptide suppression of follicle-stimulating hormone gene expression
  Journal of Biological Chemistry 2016 DOI: 10.1074/jbc.M116.740365
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