Prasad Pethe

About

Currently I am Associate Professor at Symbiosis Centre for Stem Cell Research (SCSCR), Symbiosis International University.
In my current position, I have undertaken several projects –
• Exploring the role of PcG proteins in regulating Epithelial to Mesenchymal (EMT) transition genes in human endometriosis,
• Investigating the role of histone H2A deubiquitinases during differentiation of human pluripotent stem cells into neuronal lineage

Areas of expertise:
Pluripotent stem cell differentiation, Polycomb Group (PcG) proteins, epigenetics, cell and developmental biology.

Employment

• Symbiosis International University Associate professor
  2025 - Present
• Symbiosis International (Deemed University) Assistant Professor
  2019 - 2025
• NMIMS Sunandan Divatia School of Science Assistant Professor
  2016 - 2019
• National Burns Centre Senior Researcher
  2015 - 2016

Education

• National Institute for Research in Reproductive Health PhD
  2008 - 2015

Projects & Funding

Projects & funding information is unavailable.

Publications (46)

• Cautionary tale: over-reliance on RNA sequencing data in biological research
  MINERVA BIOTECHNOLOGY AND BIOMOLECULAR RESEARCH 2026 DOI: 10.23736/S2724-542X.26.03352-3
  +Save
• Knockdown of histone H2A deubiquitinase BAP1 in human embryonic stem cells restricts their differentiation repertoire but is dispensable for maintaining their undifferentiated state
  Biochemical and Biophysical Research Communications 2026 DOI: 10.1016/j.bbrc.2026.153260
  +Save
• Histone H2A deubiquitinase BAP1 is required for human neuronal progenitor cell formation
  Differentiation 2026 DOI: 10.1016/J.DIFF.2026.100957
  +Save
• Correlation between Polycomb repressive complex proteins and epithelial-mesenchymal transition-associated genes in endometriotic tissues
  Reproductive Biology 2026 DOI: 10.1016/J.REPBIO.2025.101173
  +Save
• Engineering a cell-free bone regeneration platform using osteogenically primed MSC-EVs and nHAp-enriched IPN hydrogels
  Regenerative Medicine 2025 DOI: 10.1080/17460751.2025.2557770
  +Save
• Microsphere-Mediated Sustained Delivery of Growth Factors Stimulates Osteogenesis in Target Cells in a Three-Dimensional Microenvironment
  Journal of Biomedical Materials Research Part A 2025 DOI: 10.1002/jbm.a.37947
  +Save
• RING1B-BMI1 catalyzed dynamic H2AK119ub1 modification in response to sonic hedgehog signalling during pancreatic differentiation of human embryonic stem cells
  Scientific Reports 2025 DOI: 10.1038/S41598-025-27698-Z
  +Save
• Understanding the Activity of Mechanosensors YAP and TAZ in Differentiating Human Pluripotent Stem Cells
  2024
  +Save
• The symbiotic effect of osteoinductive extracellular vesicles and mineralized microenvironment on osteogenesis
  Journal of Biomedical Materials Research Part A 2024 DOI: 10.1002/jbm.a.37600
  +Save
• Human embryonic stem cells maintain their stemness in three-dimensional microenvironment
  In Vitro Cellular and Developmental Biology Animal 2024 DOI: 10.1007/s11626-024-00868-5
  +Save