About
Dr. Prajakta Dandekar pursued Bachelor of Pharmaceutical Sciences, M. Tech. (Bioprocess Technology) and Ph.D. (Tech.) (Bioprocess Technology) at the Department Of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai. Her doctoral research was focussed on nanoparticle engineering for improved drug delivery, where she investigated different types of polymeric nanoparticles of natural actives. Her proficiency lies in various methods involved in fabrication of polymeric nanoparticles along with good insight into various aspects of targeting; an experience with the various characterization techniques; cell culturing and assays and experience in in vivo toxicity studies and executions of pharmacodynamic evaluations.
After her doctoral work, she was employed as a Postdoctoral Fellow at the Department of Macromolecular Organic Chemistry, University of Saarland. During this tenure she was engaged in the formulation of nanoparticles of new hydrophobic starch polymers for encapsulating hydrophobic anti-cancer actives. She is the first woman scientist from India to be awarded the European Respiratory Society-Marie Curie Joint Postdoctoral Fellowship (long-term) and conducted the associated research at the Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrucken, Germany. Her research was focussed on application of novel cationic polymers for intracellular delivery of siRNA for treatment of Tuberculosis. She has authored 14 publications during this tenure. She has received various fellowships from Government of India, poster prizes and travel grants for her research during this tenure. She was selected as a part of Institute of Chemical Technology team to represent India at Indo‐UK Biotechnology YES (Young Entrepreneurship Scheme) at Oxford, United Kingdom. She has been with the editorial team of CRS Newsletter, Indian chapter, and is currently a member of Membership and Development committee, CRS Inc., USA; member CRS, Indian chapter; member of outreach committee of American College of Clinical Pharmacology, USA and member of Indian Pharmaceutical Association.
Since January 2012, she has been appointed as Dr. John Kapoor Assistant Professor in Pharmaceutical Technology at Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai. Her research interests include design of RNA nanoplexes, pulmonary diseases, cellular models and artificial organs for preclinical research.
Employment
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Institute of Chemical Technology Assistant Professor2012 - Present
Education
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Institute of Chemical Technology PhD2006 - 2009
Projects & Funding
Projects & funding information is unavailable.
Publications (78)
- Emerging therapies for lung adenocarcinoma: Mechanistic and efficacy insights from spheroid-based in vitro models Save
- A 3D microfluidic model for preclinical drug permeation studies: Advancing validation of skin-on-chip technology Save
- Application of FT-IR spectroscopy as a non-invasive multi-attribute monitoring platform for critical quality attributes in monoclonal antibodies Save
- Strategic integration of 3D Cell culture and regenerative biomedical technologies in India’s biomedical ecosystem: Aligning with the global transition toward human-relevant drug development Save
- Antioxidant excipient–mediated stabilization preserves FcγRIIIa binding and ADCC activity of rituximab Save
- Cryopreservation of human lung adenocarcinoma spheroids using MMC based cryomixtures Save
- Sterilizing bioinks: Understanding the impact of techniques on 3D bioprinting materials Save
- From Efficiency to Yield: Exploring Recent Advances in CHO Cell Line Development for Monoclonal Antibodies Save
- Enhancing monoclonal antibody stability during protein a chromatography using 2-methyl imidazolium dihydrogen phosphate Save
- Analytical techniques for screening of cannabis and derivatives from human hair specimens Save