Dushyant K. Garg

About

I am working as senior postdoc at the University of Bergen, Norway on deciphering the molecular links between two classes of neuronal maladies, namely, neuropsychiatric disorders and neurodegeneration. Previously, I worked as a senior researcher at the Jawaharlal Nehru University, New Delhi, India, and investigated self-assembly processes such as liquid-liquid phase separation (LLPS) and aggregation of an intrinsically disordered prion-like domain of TDP-43 (PLD) and a neuronal protein alpha-synuclein. My recent work shows that the aggregation and LLPS of TDP-43 PLD is uncoupled and that aggregation can also happen without an accompanying LLPS state.

Employment

• University of Bergen Postdoc
  2024 - Present
• Jawaharlal Nehru University Senior Researcher
  2023 - 2023
• Jawaharlal Nehru University Research Associate (DST-SERB)
  2022 - 2023
• Jawaharlal Nehru University Research Associate (ICMR-RA)
  2019 - 2022
• Jawaharlal Nehru University Postdoctoral Fellow (SERB-NPDF)
  2017 - 2019

Education

• Indian Institute of Technology Delhi PhD
  2009 - 2017
• University of Mysore M.Sc
  2005 - 2007

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• A30P and A30G Mutations in α-Synuclein Promote Metastable Long-Lived Aggregates with Distinct Structural Responses to EGCG
  Biochemistry 2025 DOI: 10.1021/acs.biochem.5c00518
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• Green tea polyphenol EGCG acts differentially on end-stage amyloid polymorphs of α-synuclein formed in different polyol osmolytes
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2025 DOI: 10.1016/j.bbapap.2025.141073
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• Kinetic control in amyloid polymorphism: Different agitation and solution conditions promote distinct amyloid polymorphs of alpha-synuclein
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2023 DOI: 10.1016/j.bbapap.2023.140917
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• Modulation of assembly of TDP-43 low-complexity domain by heparin: From droplets to amyloid fibrils
  Biophysical Journal 2022 DOI: 10.1016/j.bpj.2022.05.042
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• In-silico and biophysical investigation of biomolecular interaction between naringin and nsP2 of the chikungunya virus
  International Journal of Biological Macromolecules 2020 DOI: 10.1016/j.ijbiomac.2020.05.165
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• Application of a protein domain as chaperone for enhancing biological activity and stability of other proteins
  Journal of Biotechnology 2020 DOI: 10.1016/j.jbiotec.2020.01.017
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• Elucidating the functional aspects of different domains of bean common mosaic virus coat protein
  Virus Research 2019 DOI: 10.1016/j.virusres.2019.197755
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• Heterologous expression of an engineered protein domain acts as chaperone and enhances thermotolerance of Escherichia coli
  International Journal of Biological Macromolecules 2018 DOI: 10.1016/j.ijbiomac.2017.10.081
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• Hyperthermophilic l -asparaginase bypasses monomeric intermediates during folding to retain cooperativity and avoid amyloid assembly
  Archives of Biochemistry and Biophysics 2017 DOI: 10.1016/j.abb.2017.04.010
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• Clues for divergent, polymorphic amyloidogenesis through dissection of amyloid forming steps of bovine carbonic anhydrase and its critical amyloid forming stretch
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2016 DOI: 10.1016/j.bbapap.2016.03.019
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