NP
Nitin Pandey
Keck School of Medicine of USC, Keck School of Medicine of USC CA US, Banaras Hindu University, American Chemical Society
0000-0001-6124-4090
Employment
-
Keck School of Medicine of USC Assistant Professor of Research2021 - Present
-
Keck School of Medicine of USC CA US Staff Scientist2019 - 2021
-
Keck School of Medicine of USC Postdoc Research Associate2014 - 2019
Education
-
Banaras Hindu University M.Sc.2005 - 2007
-
Banaras Hindu University B.Sc.2002 - 2005
-
American Chemical Society ACS Reviewer Lab Certificate of Completion
Projects & Funding
Projects & funding information is unavailable.
Publications (29)
- Fluorescent protein tagging promotes phase separation and alters the aggregation pathway of huntingtin exon-1 Save
- TDP43 and huntingtin Exon-1 undergo a conformationally specific interaction that strongly alters the fibril formation of both proteins Save
- Sonicated fibrils of huntingtin exon-1 preferentially seed neurons and produce toxic assemblies Save
- Huntingtin fibrils with different toxicity, structure, and seeding potential can be interconverted Save
- Discovery of small molecule inhibitors of huntingtin Exon 1 aggregation by FRET-Based high-throughput screening in living cells Save
- Lipid-modulation of membrane insertion and refolding of the apoptotic inhibitor Bcl-xL Save
- Structure of membrane-bound huntingtin exon 1 reveals membrane interaction and aggregation mechanisms Save
- Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin Save
- The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms Save
- The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract Save