AB
Akarsh Bajpai
Chhatrapati Shahu Ji Maharaj University, Indian Institute of Technology Hyderabad
0000-0001-6220-4322
About
I currently work with the yeast model of TDP-43 proteinopathy. My research interest is to unravel the cellular pathways and genes/proteins involved in the causation of TDP-43 toxicity.
Employment
-
Chhatrapati Shahu Ji Maharaj University Assistant Professor2025 - Present
Education
-
Indian Institute of Technology Hyderabad Ph.D.2018 - 2025
Projects & Funding
Projects & funding information is unavailable.
Publications (7)
- Targeting oxidative stress to combat neurodegenerative diseases, amyotrophic lateral sclerosis and Huntington’s, for better brain health and recovery Save
- Therapeutic targeting of the oxidative stress generated by pathological molecular pathways in the neurodegenerative diseases, ALS and Huntington's Save
- Activation of the yeast MAP kinase, Slt2, protects against TDP-43 and TDP-25 toxicity in the Saccharomyces cerevisiae proteinopathy model Save
- Computational Insights Into the Mechanism of EGCG's Binding and Inhibition of the TDP‐43 Aggregation Save
- In silico and in vitro studies suggest epigallocatechin gallate (EGCG), a polyphenol in green tea, can bind and modulate the aggregation and cytotoxicity of the full-length TDP-43 protein implicated in TDP-43 proteinopathies Save
- In Vitro Interaction of a C-Terminal Fragment of TDP-43 Protein with Human Serum Albumin Modulates Its Aggregation Save
- Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis Save