Prashanta Kumar Panda
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Cell death mechanisms and regulation · Cancer Research and Treatments · Autophagy in Disease and Therapy
About
Dr Prashanta Kumar Panda is a Staff Scientist in the Division of Pulmonary & Critical Care Medicine, Washington University in St. Louis School of Medicine, St. Louis, USA. He received his PhD in 2017 from the National Institute of Technology, Rourkela, India, where he investigated autophagy and selective autophagy–dependent cell death in cancer. His research spans cancer metabolism, neurodegenerative disease biology, and human iPSC derived models, with recognized expertise in autophagy, apoptosis, and extracellular vesicle biology. His current work focuses on elucidating the regulatory mechanisms of autophagy and selective autophagy, particularly in the context of immune modulation in end-stage lung diseases. Currently, he serves as an Editorial Board Member for Scientific Reports (Nature Portfolio) and as an Associate Editor for Frontiers in Cell and Developmental Biology and Frontiers in Cell Death. He has also served as a Guest Editor for PLOS ONE and is currently serving as a Guest Editor for a special issue in Cells. In addition, he has served as an Editorial Board Member for Tumor Discovery. He has authored and co-authored 37 publications, including 4 book chapters, in internationally reputed journals like Clinical Cancer Research, Cell Reports, Aging Cell etc. His work has received 2,861 citations (Google Scholar), with an h-index of 26 and an i10-index of 34.
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Publications (37)
- BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation-Induced Apoptosis Save
- Residual microglia following short-term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy Save
- NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency Save
- Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells Save
- Terminalia bellirica extract induces anticancer activity through modulation of apoptosis and autophagy in oral squamous cell carcinoma Save
- Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer Save
- Role of Xenobiotic in Autophagy Inflection in Cell Death and Carcinogenesis Save
- Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases Save
- Monitoring and Measuring Mammalian Autophagy Save
- Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death Save
- p73 induction by Abrus agglutinin facilitates Snail ubiquitination to inhibit epithelial to mesenchymal transition in oral cancer Save
- Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of -catenin in colon cancer stem cells Save
- Autophagy regulates cisplatin-induced stemness and chemoresistance via the upregulation of CD44, ABCB1 and ADAM17 in oral squamous cell carcinoma Save
- PUMA dependent mitophagy by Abrus agglutinin contributes to apoptosis through ceramide generation Save
- Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death Save
- Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma Save
- Abrus agglutinin targets cancer stem-like cells by eliminating self-renewal capacity accompanied with apoptosis in oral squamous cell carcinoma Save
- ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway Save
- DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced p53-mediated apoptosis through activation of cytochrome P450/aryl hydrocarbon receptor Save
- Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a] pyrene-induced apoptosis Save