Vijay Kumar Shankar

About

Dr. Vijay Kumar Shankar is an accomplished Drug Metabolism and Pharmacokinetics (DMPK) scientist with over nine years of experience spanning pharmaceutical R&D and academic research. He earned his Ph.D. in Pharmaceutical Sciences from the University of Mississippi, specializing in pharmacokinetics, drug delivery, and the development of innovative drug formulations. Complementing his doctoral work, he holds a Bachelor’s in Pharmacy and a Master’s in Pharmacology from Rajiv Gandhi University of Health Sciences in India.

Currently, Vijay is a DMPK Scientist at Remix Therapeutics, where he plays a pivotal role in advancing RNA-targeted therapeutics. His responsibilities include leading oncology programs in the strategic design and execution of ADME studies. Previously, he served as a DMPK Scientist at C4 Therapeutics, a clinical-stage biopharmaceutical company.

Earlier in his career, Vijay gained valuable experience at Jubilant Biosys in Bengaluru, where he focused on the ADME profiling of novel chemical entities. As Deputy Head of the Bioanalytical Lab, he led the team in establishing a GLP-compliant bioanalytical facility. His strong scientific expertise includes bioanalytical method development, PBPK and PK/PD modeling for first-in-human dose predictions, and the development of novel assays to enhance in vitro–in vivo correlation.

Vijay has published over 25 peer-reviewed publications, accumulating more than 500 citations, which highlights his significant contributions to the field. He is deeply committed to translating scientific discoveries into impactful therapies, and his highly collaborative approach consistently streamlines drug discovery and development across diverse therapeutic areas.

Employment

• Remix therapeutics Inc Scientist II
  2024 - Present
• Topical Products Testing LLC Senior Scientist
  2024 - 2024
• C4 Therapeutics (United States) Research Scientist II
  2021 - 2024
• University of Mississippi Research Scientist
  2019 - 2021
• Jubilant Biosys Ltd Deputy Head
  2014 - 2015
• Jubilant Biosys Ltd Research Associate
  2011 - 2015

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (29)

• Role of saturation dynamics in driving skin permeation from topical gel formulations
  Srinath Rangappa, Srinivas Ajjarapu, Vijay Kumar Shankar +4 more
  Journal of Pharmaceutical Sciences 2026 DOI: 10.1016/j.xphs.2026.104349
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• Evaluation of Critical Quality Attributes of Topical Foam Formulations
  Srinath Rangappa, Srinivas Ajjarapu, Vijay Kumar Shankar +3 more
  AAPS PharmSciTech 2026 DOI: 10.1208/s12249-026-03338-1
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• Novel topical anandamide formulation for alleviating peripheral neuropathic pain
  International Journal of Pharmaceutics 2023 DOI: 10.1016/j.ijpharm.2023.123085
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• Development of silymarin topical formulation: In vitro and ex vivo dermal kinetics of silymarin
  International Journal of Pharmaceutics 2023 DOI: 10.1016/j.ijpharm.2022.122431
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• Metronidazole crystal patterns formed during the metamorphosis of topical carbopol gels.
  Journal of Excipients and Food Chemicals 2023
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• Polymer Coated Polymeric (PCP) Microneedles for Controlled Delivery of Drugs (Dermal and Intravitreal)
  Deeksha Jakka, Anusha Vishwanath Matadh, Vijay Kumar Shankar +2 more
  Journal of Pharmaceutical Sciences 2022 DOI: 10.1016/j.xphs.2022.05.023
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• Effect of Lipid Vehicles on Solubility, Stability, and Topical Permeation of Delta-9-Tetrahydrocannabinol
  AAPS PharmSciTech 2022 DOI: 10.1208/s12249-022-02385-8
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• Analysis of docosanol using GC/MS: Method development, validation, and application to ex vivo human skin permeation studies
  Journal of Pharmaceutical Analysis 2022 DOI: 10.1016/j.jpha.2021.08.004
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• Development and Validation of HPLC Method for Efinaconazole: Application to Human Nail Permeation Studies
  AAPS PharmSciTech 2022 DOI: 10.1208/s12249-021-02196-3
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• Development and characterization of Novel topical oil/PEG creams of voriconazole for the treatment of fungal infections
  Journal of Drug Delivery Science and Technology 2021 DOI: 10.1016/j.jddst.2021.102928
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• Chemotherapeutic Agent-Induced Vulvodynia, an Experimental Model
  AAPS PharmSciTech 2021 DOI: 10.1208/s12249-021-01969-0
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• Optimization of sulfobutyl-ether-β-cyclodextrin levels in oral formulations to enhance progesterone bioavailability
  International Journal of Pharmaceutics 2021 DOI: 10.1016/j.ijpharm.2021.120212
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• A Rapid Tool to Optimize Process Variables for Continuous Manufacturing of Metronidazole Ointment Using Melt Extrusion Technique
  AAPS PharmSciTech 2020 DOI: 10.1208/s12249-020-01808-8
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• Role of Taurine Transporter in the Retinal Uptake of Vigabatrin
  AAPS PharmSciTech 2020 DOI: 10.1208/s12249-020-01736-7
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• Topical Pilocarpine Formulation for Diagnosis of Cystic Fibrosis
  Journal of Pharmaceutical Sciences 2020 DOI: 10.1016/j.xphs.2020.01.030
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• Insight into hydroxyl radical-mediated cleavage of caged methylene blue: the role of Fenton's catalyst for antimalarial hybrid drug activation
  Huy Minh Dao, Islam Husain, Vijay Kumar Shankar +3 more
  Chemical Communications 2020 DOI: 10.1039/D0CC05204C
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• Preparation and evaluation of cefuroxime axetil gastro-retentive floating drug delivery system via hot melt extrusion technology
  International Journal of Pharmaceutics 2019 DOI: 10.1016/j.ijpharm.2019.06.021
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• Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and in vivo studies
  International Journal of Pharmaceutics 2019 DOI: 10.1016/j.ijpharm.2018.11.005
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• Water Activity and Its Significance in Topical Dosage Forms
  Journal of Pharmaceutical Sciences 2018 DOI: 10.1016/j.xphs.2018.02.013
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• RP-HPLC method for simultaneous estimation of vigabatrin, gamma-aminobutyric acid and taurine in biological samples
  Journal of Chromatography B 2018 DOI: 10.1016/j.jchromb.2018.01.010
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