MANDEEP KAUR

About

I am a postdoctoral researcher at Thomas Jefferson University, where I am leading a project funded by the U.S. Department of Defense investigating the therapeutic potential of platelet-derived extracellular vesicles (EVs) for mitigating ALS progression. With a PhD in neuroanatomy and neurology, I specialize in studying neurovascular integrity in neurological disorders. My current research focuses on using EVs to restore neurovascular function and prevent neuroinflammation, aiming to translate these findings into therapeutic strategies. Passionate about bridging basic science and clinical application, I strive to contribute meaningful advancements in neuroprotection and developing innovative treatments for devastating neurodegenerative diseases.

Employment

• Thomas Jefferson University Postdoctoral Researcher
  2022 - Present
• Post Graduate Institute of Medical Education and Research PhD Scholar
  2017 - 2021

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (13)

• Donor sex and platelet storage change the therapeutic effects of platelet-derived extracellular vesicles on endothelium
  Mandeep Kaur, Malvika Gupta, Sowmya Shree Gopal

  +3 more

  • Charles E. Wade
  • Jessica C. Cardenas
  • Amit K. Srivastava
  Blood Vessels, Thrombosis & Hemostasis 2026 DOI: 10.1016/j.bvth.2026.100148
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• Optimization of platelet-derived extracellular vesicle preparation for hemostatic efficacy during major traumatic hemorrhage
  Ava K. Mokhtari, Sowmya Shree Gopal, Mandeep Kaur

  +5 more

  • Baron K. Osborn
  • Marissa D. Pokharel
  • Charles E. Wade
  • Amit K. Srivastava
  • Jessica C. Cardenas
  Shock 2026 DOI: 10.1097/shk.0000000000002823
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• The Breakdown of Neurovascular Barriers: Molecular Mechanisms of Tight Junction Dysfunction
  Sowmya Shree Gopal, Mandeep Kaur, Sophie Lanzkron

  +1 more

  • Amit K. Srivastava
  Molecular Neurobiology 2026 DOI: 10.1007/s12035-025-05592-z
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• Most recent advances and applications of extracellular vesicles in tackling neurological challenges.
  Mandeep Kaur, Salvatore Fusco, Bram Van den Broek

  +6 more

  • Jaya Aseervatham
  • Abdolmohamad M. Rostami
  • Lorraine Iacovitti
  • Claudio Grassi
  • Barbara Łukomska
  • +1 more
  Medicinal research reviews 2024 DOI: 10.1002/med.22035
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• Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires repeated handling
  Yolanda Gómez‐Gálvez, Malvika Gupta, Mandeep Kaur

  +6 more

  • Salvatore Fusco
  • Maria Vittoria Podda
  • Claudio Grassi
  • Amit K. Srivastava
  • Lorraine Iacovitti
  • +1 more
  PLOS ONE 2024 DOI: 10.1371/JOURNAL.PONE.0312298
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• Analysis of distribution and localization of proteins of the reelin signalling pathway in mesial temporal lobe epilepsy.
  The International journal of neuroscience 2023 DOI: 10.1080/00207454.2023.2292957
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• Expressional Study of Permeability Glycoprotein and Multidrug Resistance Protein 1 in Drug-resistant Mesial Temporal Lobe Epilepsy
  Basic and Clinical Neuroscience Journal 2023 DOI: 10.32598/bcn.2021.2554.3
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• Central myelin-peripheral myelin junction in trigeminal, facial, and vestibulocochlear nerve: A histo-morphometric study.
  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 DOI: 10.1016/j.aanat.2023.152128
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• Investigating the Glucagon-like Peptide-1 and Its Receptor in Human Brain: Distribution of Expression, Functional Implications, Age-related Changes and Species Specific Characteristics.
  Basic and clinical neuroscience 2023 DOI: 10.32598/bcn.2021.2554.2
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• Reelin Signaling Pathway and Mesial Temporal Lobe Epilepsy: A Causative Link.
  Tulika Gupta, Mandeep Kaur, Navneet Singla

  +4 more

  • Bishan Dass Radotra
  • Daisy Sahni
  • Parampreet Singh Kharbanda
  • Sunil K Gupta
  Basic and clinical neuroscience 2023 DOI: 10.32598/bcn.2021.2554.1
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• Identification of novel pulmonary vein nodes as generators of ectopic arrhythmic foci for atrial fibrillation: an immunohistochemical proof.
  Surgical and radiologic anatomy : SRA 2022 DOI: 10.1007/s00276-021-02864-w
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• Role of drug-efflux transporter in drug-resistant Mesial Temporal Lobe Epilepsy
  3rd CME & Conference of North Chapter of Anatomists Society (NCAS), Department of Anatomy, PGIMER, Chandigarh 2021
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• Immunohistochemical analysis of Reelin signaling pathway in Mesial Temporal Lobe Epilepsy
  14th Annual CME-cum- Conference of North State Chapter of Anatomical Society of India. DMCH, Ludhiana 2019
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