IM
Ira Milosevic
University of Oxford, Universidade de Coimbra Multidisciplinary Institute of Ageing, Georg-August-Universität Göttingen, Max Planck Institute for Biophysical Chemistry, University of Zagreb
Employment
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Universidade de Coimbra Multidisciplinary Institute of Ageing Research coordinator2022 - 2024
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European Neuroscience Institute Göttingen PI2013 - 2021
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Yale University School of Medicine postdoc2007 - 2011
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Max Planck Institute for Biophysical Chemistry MSc student and PhD student and postdoc2002 - 2006
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University of Oxford
Education
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Georg-August-Universität Göttingen PhD2003 - 2006
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Max Planck Institute for Biophysical Chemistry MSc2001 - 2003
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University of Zagreb Dipl Ing1996 - 2001
Projects & Funding
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Endosomal sub-compartments in health and disease Centro de la Fundació Caixa Castelló2022 - 2025
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Novel mechanisms of v-ATPase regulation in vertebrates Wellcome Trust2022 - 2029
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A maturacao da vesicula sinaptica e a sua relevancia para a neurodegeneracao Fundação para a Ciência e a Tecnologia2021 - 2024
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John Black Senior Research Fellowship in Parkinson's Disease N/A2020 - Present
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Characterization of mitochondria-ER contact sites and their role in cellular signalling (P02) German Research Foundation2016 - Present
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The role of phosphoinositides in platelet formation Croatian Science Foundation2016 - 2019
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Dynamic Membrane Traffic at the Neuronal Synapse Schram Stiftung2016 - 2021
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Molecular physiology of synaptic vesicle recycling at the hair cell ribbon synapse (A08*) Deutsche Forschungsgemeinschaft2015 - Present
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Pathological mechanisms of synaptic vesicle recycling German Research Foundation2012 - Present
Publications (67)
- Dynamins maintain nuclear envelope homeostasis and genome stability Save
- Dopamine release from Parkinson’s patient-derived neurons is disrupted due to impaired synaptic vesicle loading Save
- Nucleophagy removes cytotoxic trapped PARP1 Save
- Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling Save
- Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment Save
- Role of lipids in interorganelle communication Save
- Upregulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain Save
- Up-regulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain Save
- Role of lipids in inter-organelle communication Save
- Genetic modulation of E3-ubiquitin ligase FBXO32 rescues dopaminergic pathology in endophilin-A mutant mice Save