Hope Pan

Employment

• Stanford Health Care Resident
  2026 - Present

Education

• UCLA PhD
  2020 - 2024
• UCLA MD
  2018 - 2026
• Vanderbilt University Bachelor of Arts, Chemistry and Applied Mathematics

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• In Vitro and In Vivo Evaluation of Small-Molecule Disassemblers of Pathological Tau Fibrils
  ACS Chemical Neuroscience 2026 DOI: 10.1021/acschemneuro.5c00940
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• Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein.
  NPJ Parkinson's disease 2025 DOI: 10.1038/s41531-025-00918-z
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• D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease.
  Science advances 2024 DOI: 10.1126/sciadv.adl2991
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• Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
  Proceedings of the National Academy of Sciences of the United States of America 2023 DOI: 10.1073/pnas.2300258120
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• Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
  Nature communications 2023 DOI: 10.1038/s41467-023-37865-3
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• Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
  Proceedings of the National Academy of Sciences of the United States of America 2023 DOI: 10.1073/pnas.2217835120
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• Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
  Nature communications 2022 DOI: 10.1038/s41467-022-32951-4
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• De novo designed protein inhibitors of amyloid aggregation and seeding.
  Proceedings of the National Academy of Sciences of the United States of America 2022 DOI: 10.1073/pnas.2206240119
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• Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
  Nature structural & molecular biology 2022 DOI: 10.1038/s41594-022-00774-y
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• Minocycline alleviates depression-like symptoms by rescuing decrease in neurogenesis in dorsal hippocampus via blocking microglia activation/phagocytosis.
  Brain, behavior, and immunity 2020 DOI: 10.1016/j.bbi.2020.11.009
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