Karthikeyan Dharmapuri Rajamani

About

I am very passionate about biomedical research. My area of focus is in oxidative stress, chronic diseases, from basic to advanced screening. My research interests aimed towards the fundamental questions on molecular markers that link early detection and prevention of vascular injuries. I have developed strong interests in carcinogenesis, toxicology and environmental health in the evolution of human biomonitoring. I approach through the realm of analytical biochemistry, translational biology and cytogenetics to decipher how metabolic perturbation can lead to organ damage. I seek to develop bio-markers that play an vital role in diagnosis and prognosis through non-invasive sampling techniques, whilst maximizing the quality of life.

Employment

• Sri Ramachandra Institute of Higher Education and Research Senior Research Scientist
  2017 - Present
• V ClinBio Labs Pvt. Ltd. Research Coordinator
  2016 - 2017
• Sri Ramachandra Institute of Higher Education and Research Project Coordinator
  2014 - 2015
• University of British Columbia Post Doctoral Fellow
  2011 - 2014
• Annamalai University Project Assistant
  2009 - 2011
• Annamalai University Junior Research Fellow & Senior Research Fellow (DST Project)
  2006 - 2009
• Kanchi Kamakoti Childs Trust Hospital Cytogenetician
  2005 - 2006

Education

• Annamalai University PhD-Marine Biotechnology
  2009 - 2012
• Annamalai University M.Phil- Marine Biology
  2007 - 2009
• Sri Ramachandra Institute of Higher Education and Research MSc-Human Genetics
  2003 - 2005
• Kongunadu Arts and Science College BSc-Biotechnology
  2000 - 2003

Projects & Funding

Projects & funding information is unavailable.

Publications (13)

• Squalene deters drivers of RCC disease progression beyond VHL status
  Cell Biology and Toxicology 2021 DOI: 10.1007/s10565-020-09566-w
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• Variability In Linear Polypeptide Stabilizes Proteoglycan Than Zinc Finger Protein in Vascular Smooth Muscle Cells: An In Silico Approach
  Biomedical and Biotechnology Research Journal 2021
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• Computational Characterization of Human Vascular Endothelial Growth Factor Proteins
  Bioscience Biotechnology Research Communications 2020 DOI: 10.21786/bbrc/13.2/51
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• Applications of Feather Keratin Hydrolysate in Divergent Fields
  Bioscience Biotechnology Research Communications 2019 DOI: 10.21786/bbrc/12.4/30
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• Bioassay-guided isolation of triterpene from brown alga Padina boergesenii possess anti-inflammatory and anti-angiogenic potential with kinetic inhibition of β-carotene linoleate system
  LWT 2018 DOI: 10.1016/j.lwt.2018.04.010
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• Polyphenols from brown alga, Padina boergesenii (Allendar & Kraft) decelerates renal cancer growth involving cell cycle arrest and induction of apoptosis in renal carcinoma cells
  Environmental Toxicology 2018 DOI: 10.1002/tox.22619
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• Ameliorative effect of polyphenols fromPadina boergeseniiagainst ferric nitrilotriacetate induced renal oxidative damage: With inhibition of oxidative hemolysis andin vitrofree radicals
  Environmental Toxicology 2015 DOI: 10.1002/tox.21951
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• Clinical, biochemical, and genetic predictors of coronary artery bypass graft failure
  The Journal of Thoracic and Cardiovascular Surgery 2014 DOI: 10.1016/j.jtcvs.2013.10.011
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• Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD
  JAMA 2013 DOI: 10.1001/jama.2013.277064
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• Clinical, Biochemical and Genetic Predictors of Late Coronary Artery Bypass Graft Failure
  Circulation 2012
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