Mendes AM

Employment

• Instituto de Medicina Molecular Post-doctoral researcher
  2018 - Present
• Instituto de Medicina Molecular Post-doctoral fellow
  2013 - 2018
• Instituto de Medicina Molecular Post-doctoral fellow
  2011 - 2013

Education

Education history is unavailable.

Projects & Funding

• Malaria drug resistance: treatment alternatives and optimization – a project strengthening a national reference centre for anti-malarial clinical trials and capacity building in Angola Aga Khan Foundation
  2018 - Present
• Enabling strategies for enhanced whole-sporozoite malaria vaccines / Estratégias para o desenvolvimento e melhoramento de vacinas de organismo inteiro contra a malária Fundação para a Ciência e a Tecnologia
  2018 - 2021
• Safety and protective efficacy of genetically modified Plasmodium berghei (Pb(PfCS@UIS4)) malaria parasites in healthy volunteers PATH Malaria Vaccine Initiative
  2017 - 2019
• Improving whole organism vaccines against malaria by genetic modification / Melhoramento de vacinas de organismo inteiro contra a malária por modificação genética Fundação para a Ciência e a Tecnologia
  2016 - 2019
• A P. berghei-based vaccine against Malaria / Uma vacina contra a malária baseada em P. berghei PATH Malaria Vaccine Initiative
  2015 - 2017
• Utilization of host cell resources by the malaria parasite in the liver / Utilização dos recursos da célula hospedeira pelo parasita da malária no fígado Fundação para a Ciência e a Tecnologia
  2012 - 2015
• EXPLORING HOST-PARASITE INTERACTIONS TO ESTABLISH A NEW WHOLE ORGANISM VACCINE AGAINST MALARIA Fundação para a Ciência e a Tecnologia
  2012 - 2018
• EMBL INTERNATIONAL PHD PROGRAMME ON BIOLOGY AND PATHOLOGY OF THE MALARIA PARASITE (BIOMALPAR) European Commission
  2005 - 2019

Publications (37)

• Host cell traversal by Plasmodium parasites is essential for sterilizing hepatic cellular immunity
  2026 DOI: 10.64898/2026.03.20.713177
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• Variable long-term protection by radiation-, chemo-, and genetically-attenuated Plasmodium berghei sporozoite vaccines
  Vaccine 2023 DOI: 10.1016/j.vaccine.2023.11.023
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• The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria
  npj Vaccines 2023 DOI: 10.1038/s41541-023-00778-9
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• A genetically modified Plasmodium berghei parasite as a surrogate for whole-sporozoite vaccination against P. vivax malaria
  npj Vaccines 2022 DOI: 10.1038/s41541-022-00585-8
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• Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver.
  Blandine M. D. Franke-Fayard, Catherin Marin-Mogollon, Fiona J. A. Geurten

  +28 more

  • Séverine Chevalley
  • Jai Ramesar
  • Hans Kroeze
  • Els Baalbergen
  • Els Wessels
  • +23 more
  NPJ vaccines 2022 DOI: 10.1038/s41541-022-00558-x
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• Impact of Dietary Protein Restriction on the Immunogenicity and Efficacy of Whole-Sporozoite Malaria Vaccination.
  Frontiers in immunology 2022 DOI: 10.3389/fimmu.2022.869757
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• Using the Hurst Exponent and Entropy Measures to Predict Effective Transmissibility in Empirical Series of Malaria Incidence
  Applied Sciences 2022 DOI: 10.3390/app12010496
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• A guide to investigating immune responses elicited by whole-sporozoite pre-erythrocytic vaccines against malaria.
  The FEBS journal 2021 DOI: 10.1111/febs.16016
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• A Model for Assessing the Quantitative Effects of Heterogeneous Affinity in Malaria Transmission along with Ivermectin Mass Administration
  Applied Sciences 2020 DOI: 10.3390/app10238696
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• Generation of a Genetically Modified Chimeric Plasmodium falciparum Parasite Expressing Plasmodium vivax Circumsporozoite Protein for Malaria Vaccine Development.
  Yukiko Miyazaki, Catherin Marin-Mogollon, Takashi Imai

  +18 more

  • António M. Mendes
  • Rianne van der Laak
  • Angelika Sturm
  • Fiona J. A. Geurten
  • Shinya Miyazaki
  • +13 more
  Frontiers in cellular and infection microbiology 2020 DOI: 10.3389/fcimb.2020.591046
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• Elimination of Hepatic Rodent Plasmodium Parasites by Amino Acid Supplementation.
  iScience 2020 DOI: 10.1016/j.isci.2020.101781
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• Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers
  2020 DOI: 10.1002/eji.202048970
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• An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against Plasmodium falciparum malaria
  Science Translational Medicine 2020 DOI: 10.1126/scitranslmed.aay2578
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• Molecular Design and Synthesis of Ivermectin Hybrids Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites.
  Journal of medicinal chemistry 2020
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• Transition from endemic behavior to eradication of malaria due to combined drug therapies: An agent-model approach
  Journal of Theoretical Biology 2020 DOI: 10.1016/j.jtbi.2019.110030
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• Inhibition of Plasmodium sporogonic stages by ivermectin and other avermectins.
  Parasites & vectors 2019 DOI: 10.1186/s13071-019-3805-0
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• Trypanosoma brucei infection protects mice against malaria
  PLOS Pathogens 2019 DOI: 10.1371/journal.ppat.1008145
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• The Impact of Antiretroviral Therapy on Malaria Parasite Transmission.
  Frontiers in microbiology 2019 DOI: 10.3389/fmicb.2019.03048
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• Pre-clinical evaluation of a P. berghei-based whole-sporozoite malaria vaccine candidate
  npj Vaccines 2018 DOI: 10.1038/s41541-018-0091-3
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• A Plasmodium berghei sporozoite-based vaccination platform against human malaria.
  António M. Mendes, Marta Machado, Nataniel Gonçalves‐Rosa +22 more
  NPJ vaccines 2018 DOI: 10.1038/s41541-018-0068-2
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