Sofia Ali
National University Biomedical Research Institute/ National University-Sudan
0000-0001-6718-3540
About
Dr. Sofia Bashir Mohamed Ali is an Associate Professor of Molecular Biology and Bioinformatics with more than 15 years of experience in pathogen genomics, antimicrobial resistance (AMR), and genomic surveillance system development. She is the Director and Co-Founder of the National University Biomedical Research Institute (NUBRI), Sudan, where she leads initiatives to establish genomic surveillance and bioinformatics infrastructure supporting infectious disease research and public health programs.
Her research focuses on the application of whole-genome sequencing (WGS), molecular epidemiology, and bioinformatics to investigate microbial evolution, antimicrobial resistance mechanisms, and pathogen transmission dynamics. She has extensive experience in next-generation sequencing technologies and downstream genomic analyses, including mutation detection, comparative genomics, and genotype–phenotype integration.
Dr. Ali founded Galaxy-NUBRI and VBCRI-Sudan, digital research platforms designed to enable standardized, reproducible, and interoperable genomic analysis workflows and strengthen genomic research capacity in low- and middle-income countries. Her work integrates microbial genomics, mutation analysis, and genomic data interpretation to support infectious disease surveillance and evidence-based decision making.
In addition to pathogen genomics, her research includes computational drug discovery and structural bioinformatics. As a DAR Research Fellow at Qatar University, she is leading a research project focused on computational discovery of novel therapeutic compounds targeting breast cancer–associated genes, using mutation analysis, molecular docking, and structure-based drug design approaches.
She has trained and mentored hundreds of researchers and health professionals in genomics, bioinformatics, and molecular epidemiology, contributing to the development of sustainable scientific capacity and genomic surveillance systems in resource-constrained settings
Employment
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National University Biomedical Research Institute/ National University-Sudan Co-founder and Director2020 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (21)
- Green Synthesis of Silver Nanoparticles Using Sudanese Candida parapsilosis: A Sustainable Approach to Combat Antimicrobial Resistance Save
- The impact of mutations on TP53 protein and MicroRNA expression in HNSCC: Novel insights for diagnostic and therapeutic strategies Save
- Whole-genome sequence data of a Salmonella enterica serovar Rissen sequence type 8877 isolated from cracked table egg in Sudan Save
- Bioinformatics in Sudan: Status and challenges case study: The National University-Sudan Save
- Virulence and antimicrobial resistance of Klebsiella pneumoniae strain NUBRI-K (ST14), Sudan. Save
- Molecular Detection of Occult Hepatitis B virus in plasma and urine of renal transplant patients in Khartoum state Sudan Save
- Genome Sequence of Escherichia coli Clone O25:H4 Sequence Type 131, Isolated from a Sudanese Patient with Urinary Tract Infection Save
- NeoCoV Is Closer to MERS-CoV than SARS-CoV Save
- First Whole-Genome Sequence of a Highly Resistant Klebsiella pneumoniae Sequence Type 14 Strain Isolated from Sudan Save
- Proteomics and Docking Study Targeting Penicillin-Binding Protein and Penicillin-Binding Protein2a of Methicillin-Resistant Staphylococcus aureus Strain SO-1977 Isolated from Sudan Save