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Ekaterina Semenova
Rutgers, The State University of New Jersey, Institute of Cytology and Genetics
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Bacterial Genetics and Biotechnology · CRISPR and Genetic Engineering · Bacteriophages and microbial interactions
Employment
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Rutgers, The State University of New Jersey Research Assistant Professor, Lab Director
Education
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Institute of Cytology and Genetics PhD, genetics? - 2002
Projects & Funding
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The Function of Small RNA-Based viral Defense System in E. coli - Renewal 1 National Institute of General Medical Sciences2013 - 2025
Publications (52)
- tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector Save
- Identification of an anti-CRISPR protein that inhibits the CRISPR-Cas type I-B system in Clostridioides difficile. Save
- CRISPR-Cas Controls Cryptic Prophages. Save
- Host nucleases generate prespacers for primed adaptation in the E. coli type I-E CRISPR-Cas system Save
- Persistence of plasmids targeted by CRISPR interference in bacterial populations Save
- Protospacer-Adjacent Motif Specificity during Clostridioides difficile Type I-B CRISPR-Cas Interference and Adaptation. Save
- Prespacers formed during primed adaptation associate with the Cas1–Cas2 adaptation complex and the Cas3 interference nuclease–helicase Save
- Reproducible Antigen Recognition by the Type I-F CRISPR-Cas System Save
- Detection of spacer precursors formed in vivo during primed CRISPR adaptation Save
- Systematic analysis of Type I‐E Escherichia coli CRISPR‐Cas PAM sequences ability to promote interference and primed adaptation Save
- Defining the seed sequence of the Cas12b CRISPR-Cas effector complex Save
- Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation Save
- The action ofEscherichia coliCRISPR–Cas system on lytic bacteriophages with different lifestyles and development strategies Save
- Altered stoichiometryEscherichia coliCascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation Save
- Come Together: CRISPR-Cas Immunity Senses the Quorum Save
- The Influence of Copy-Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense Save
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector Save
- Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complex Save
- Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3′-terminal segment of guide RNA Save
- Foreign DNA acquisition by the I-F CRISPR–Cas system requires all components of the interference machinery Save