Jagat C. Borah, Ph.D.
National Institute of Pharmaceutical Education and Research, Institute of Advanced Study in Science and Technology, Icahn School of Medicine at Mount Sinai
About
Currently Professor at National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India.
Education and Training: MSc in Chemistry (Organic), PhD in Total Synthesis of Bioactive Natural Products (CSIR-NEIST, Jorhat, Assam, India), Postdoc in Chemical Biology (Icahn School of Medicine at Mount Sinai, New York City, USA).
Research Area: Traditional Medicine, Natural Products, Synthetic Organic and Medicinal Chemistry, Chemical Biology, Pharmacology and Phytopharmaceutical Drug Development.
Taking a clue of the global trends and opportunities in plant based medicines, in India, Drug Controller General of India (DCGI of CDSCO) promulgated Phytopharmaceutical drug and published in the Gazette Notification in the year 2015. Our group is working on preclinical evaluation of selected medicinal plants based on Indian Systems of Medicine (ISM) used for the treatment of Diabetes and Diabetic Nephropathy with an aimed for the Development of Phytopharmaceutical Drug.
Specialism: Extraction, isolation and structure elucidation of pure molecules from natural sources by using different chromatographic and spectroscopic techniques, qualitative and quantitative analysis of natural products by HPLC, preparation of enriched and standardized fraction based on marker compounds, as well as interpretation of NMR spectra (1H, 13C, HSQC, COSY, HMBC, NOESY etc), LC-MS/MS, GC-MS, FTIR for structure elucidation of small molecules. In vitro and in vivo studies for development of small molecules / phytopharmaceuticals for the management of Type 2 diabetes and diabetic nephropathy.
Employment
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National Institute of Pharmaceutical Education and Research Professor2024 - Present
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Institute of Advanced Study in Science and Technology Professor2024 - 2024
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Institute of Advanced Study in Science and Technology Associate Professor2018 - 2023
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North East Institute of Science and Technology CSIR Principal Scientist2016 - 2018
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Institute of Bioresources and Sustainable Development Scientist2012 - 2016
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Phyto Biotech Pvt. Ltd. Principal Scientist2012 - 2012
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GBP Incubation Centre Sr. Research Scientist2009 - 2011
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Icahn School of Medicine at Mount Sinai Postdoctoral Research Fellow2006 - 2008
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Chemgen Pharam Int. Pvt. Ltd. Research Scientist2005 - 2006
Education
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Icahn School of Medicine at Mount Sinai Postdoctoral Research2006 - 2008
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CSIR - North East Institute of Science and Technology Ph.D.2001 - 2006
Projects & Funding
Projects & funding information is unavailable.
Publications (89)
- Bioactive compounds of Glycyrrhiza glabra and their functional role in modulating gut inflammation and intestinal homeostasis Save
- Protopine-Enriched Dactylicapnos Scandens Root Fraction Improves Glucose Homeostasis in Cell and Mouse Models Via AMPK/PEPCK/G6Pase Modulation Save
- Novel Thiazolyl-2-(N-Sulfonyl) Guanidines as Potential Anticancer Leads Targeting Caspase-9: Synthesis, Apoptosis Induction, and In Silico Profiling Save
- Regioselective N2-Arylation of Tetrazoles under CuO nanocatalysis: A route to potent anti-MRSA agents Save
- Banana Nanofiber-Based Biopolymer Patch with Trimetallic Nanoparticles for Wound Healing Save
- Review on Advancement of AI in Cell Engineering and Molecular Biology Save
- Verbascoside as a potential SGLT2 inhibitor in diabetic nephropathy: Targeting AMPK activation to suppress NOX4/NF-κB signaling and attenuate inflammation and fibrosis Save
- Synthesis of Thiazole-linked N-Sulfonyl Guanidines as Apoptosis-Inducing Anti-Cancer Agents. Indian Patent Application No. 202531008729 . Save
- Sodium Alginate-chitosan-starch based glue formulation for sealing biopolymer films Save
- Ficus Palmata Plant Extract and its Bioactive Compound from Water Extract for Alpha-Glucosidase Inhibitory Activity. Indian Patent Application No. 202531022800 Save