MS
Mengcheng Shen
Also known as: Simon Shen
Washington University in St. Louis, Stanford University, University of Alberta
Research areas: Medicine · Cardiology and Cardiovascular Medicine · Cardiac Valve Diseases and Treatments · Aortic Disease and Treatment Approaches · Pluripotent Stem Cells Research
0000-0001-7037-6159
Employment
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Washington University in St. Louis Assistant Professor2025 - Present
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Stanford University Instructor2023 - 2025
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Stanford University Postdoctoral Fellow2018 - 2023
Education
- 2012 - 2018
Projects & Funding
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A Human iPSC-based Platform to Unravel the Role of Nicotine in the Pathogenesis of Abdominal Aortic Aneurysms TRDRP
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Elucidating anti-angiogenic tyrosine kinase inhibitor-induced vascular dysfunction National Institutes of Health
Publications (28)
- Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization Save
- Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells. Save
- Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytes. Save
- Protocol to generate cardiac pericytes from human induced pluripotent stem cells. Save
- Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction. Save
- Statins improve endothelial function via suppression of epigenetic-driven EndMT. Save
- Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease. Save
- Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying TTN mutations. Save
- Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Save
- Generation of Embryonic Origin-Specific Vascular Smooth Muscle Cells from Human Induced Pluripotent Stem Cells. Save
- Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. Save
- Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying TNNI3 mutations. Save
- The Regulation of Endothelial Function Through Hmgcr/mevalonate Pathway Mediated Yap Activity Save
- Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells. Save
- Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. Save
- Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Save
- Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm Save
- Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm Save
- TIMP3 deficiency exacerbates iron overload-mediated cardiomyopathy and liver disease. Save
- Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage. Save