KUNTAL PAL

About

I am a PhD in Structural biology with M.Tech in Biotechnology and Biochem Engineering. After pursued my M. Tech from IIT-Kharagpur, India in 2006 I joined Department of Biological Science, National University of Singapore for my PhD on Structure Biology. In Macromolecular Crystallography lab of DBS, NUS under the guidance of Prof. Swaminathan I was trained in protein biochemistry and crystallography. In 2011, I joined Structural Biology lab of Prof (Distinguished) Eric Xu in Van Andel Institute, Michigan. There I mainly worked on GPCRs and receptor tyrosine kinase MET. My work was published in several peer review journals which includes Nature, Cell and JBC. Among my work the most relevant one is crystal structure of Rhodopsin-arrestin, cryo-EM model of Rhodopsin-G protein receptor kinase and cryo-EM structure of GPCR-beta Arrestin complex.

Employment

• Vellore Institute of Technology University Associate Professor II
  2023 - Present
• Adamas University Associate Professor
  2021 - Present
• Adamas University Assistant Professor
  2018 - 2021
• Van Andel Research Institute Post Doctoral fellow
  2011 - 2017

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (15)

• Understanding the Molecular Regulation of Serotonin Receptor 5-HTR1B-β-Arrestin1 Complex in Stress and Anxiety Disorders.
  Journal of molecular neuroscience : MN 2023 DOI: 10.1007/s12031-023-02146-7
  +Save
• miRNA regulation of G protein-coupled receptor mediated angiogenic pathways in cancer
  The Nucelus 2021
  +Save
• A complex structure of arrestin-2 bound to a G protein-coupled receptor.
  Cell research 2019 DOI: 10.1038/s41422-019-0256-2
  +Save
• Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
  Cell 2017 DOI: 10.1016/j.cell.2017.07.002
  +Save
• Molecular assembly of rhodopsin with G protein-coupled receptor kinases.
  Cell research 2017 DOI: 10.1038/cr.2017.72
  +Save
• Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.
  Structure (London, England : 1993) 2017 DOI: 10.1016/j.str.2017.04.015
  +Save
• Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.
  The Journal of biological chemistry 2016 DOI: 10.1074/jbc.M116.726620
  +Save
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
  Nature 2015 DOI: 10.1038/nature14656
  +Save
• Upregulation of glycans containing 3' fucose in a subset of pancreatic cancers uncovered using fusion-tagged lectins.
  Journal of proteome research 2015 DOI: 10.1021/acs.jproteome.5b00142
  +Save
• Structure modeling using genetically engineered crosslinking.
  Cell 2013 DOI: 10.1016/j.cell.2013.11.018
  +Save