Ryan Smith

Employment

• TruDiagnostic Founder
  2020 - Present

Education

• University of Kentucky Medical Center
  2013 - 2015

Projects & Funding

Projects & funding information is unavailable.

Publications (22)

• Regulatory mode and enhancer architecture determine limits of blood DNA methylation as a molecular proxy
  2026 DOI: 10.64898/2026.07.14.738581
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• Brain-targeted epigenetic effects of two emerging psychoplastogens: ketamine & MDMA
  Translational Psychiatry 2026 DOI: 10.1038/s41398-026-04191-3
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• Methylome-wide association study in blood suggests cell type-specific relationships between DNA methylation and lifetime anxiety
  Nature Communications 2026 DOI: 10.1038/s41467-026-73367-8
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• A large-scale DNA methylation study of alcohol use identified robust associations and cell-type specific insights
  Molecular Psychiatry 2026 DOI: 10.1038/s41380-026-03477-8
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• Semaglutide slows epigenetic aging in a randomized trial of HIV-associated lipohypertrophy
  Nature Communications 2026 DOI: 10.1038/s41467-026-72861-3
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• The Epigenetic Fingerprint of Lifestyle: Smoking, Vaping, and Exercise Revealed Through Buccal DNA Methylation
  Genes 2026 DOI: 10.3390/genes17040369
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• Skin DNA Methylation Encodes Multidimensional Facial Aging Phenotypes with Distinct Biological Architectures
  2026 DOI: 10.64898/2026.03.13.711642
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• Plasticity of X-chromosome inactivation in female reproduction
  2026 DOI: 10.21203/rs.3.rs-8764864/v1
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• Effect of Pitavastatin on Epigenetic Aging Biomarkers in People With HIV: Pilot Substudy of the REPRIEVE Trial
  Clinical Infectious Diseases 2026 DOI: 10.1093/cid/ciaf247
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• Responsiveness of epigenetic aging biomarkers to longevity interventions in humans
  Nature Medicine 2026 DOI: 10.1038/s41591-026-04562-9
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