Amit Kumar Chakraborty
Boston University, North East Institute of Science and Technology CSIR, Assam University, Lovely Professional University, ICAR Research Complex for North Eastern Hill Region
0000-0001-7455-6579
About
Accomplished cancer biologist and Postdoctoral Associate with extensive expertise in tumor immunology, epigenetics, and advanced bioinformatics. Proven success in unraveling the epigenetic regulation of the Head and Neck Squamous Cell Carcinoma (HNSCC) tumor microenvironment, highlighted by recent high-impact publications in Cancer Research and International Journal of Oral Science. Skilled in bridging wet-lab experiments including complex in vivo murine models and multiparameter flow cytometry with dry-lab multi-omics data analysis. Proficient in utilizing R programming packages (such as Seurat, DESeq2, and CellChat) for scRNA-seq, proteomics, and transcriptomics analyses to drive translational discoveries in immunotherapy and targeted treatments.
Employment
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Boston University Postdoctoral Associate2022 - Present
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North East Institute of Science and Technology CSIR Project Scientist II2020 - Present
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ICAR Research Complex for North Eastern Hill Region Senior Research Fellow2014 - 2020
Education
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Assam University Ph.D.2012 - 2018
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Lovely Professional University M.Sc.2009 - 2011
Projects & Funding
Projects & funding information is unavailable.
Publications (18)
- LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma Save
- LOXL2 deletion triggers TMJ osteoarthritis, while overexpression protects it from NF-κB-induced chondrocyte apoptosis Save
- Constructing a cross-tissue human knee single-cell atlas identified osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages Save
- Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression Save
- LOXL2 alleviates post-traumatic knee osteoarthritis and pain Save
- LOXL2 Deletion Triggers TMJ Osteoarthritis While Overexpression Protects Against NF-κβ-Induced Chondrocyte Apoptosis Save
- Unique TMJ-specific transcriptomic signature and its medial layer: Implications in osteoarthritis Save
- Clinical data investigation identifies MARK3 as an oncogenic driver in castration-resistant prostate cancer Save
- A multi-tissue human knee single-cell atlas identifies that osteoarthritis reduces regenerative tissue stem cells while increasing inflammatory pain macrophages Save
- The unique molecular signature of TMJ as compared to the knee, demonstrates its susceptibility to osteoarthritis Save