Sonam
Also known as: Sonam
The Ohio State University, Birla Institute of Technology and Science, Pilani, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, University of Delhi
Research areas: Chemistry · Inorganic Chemistry · Crystal structures of chemical compounds · Crystallography and molecular interactions · Crystal Structures and Properties
0000-0001-7613-7642
About
My doctoral work is mainly based on the synthetic organic chemistry (metal-free and transition metal catalyzed reactions) and photo-redox chemistry for which I have successfully developed new synthetic protocols by employing transition metal-catalyzed and metal-free C-H functionalization reactions.
In my postdoctoral research, I work on synthesizing cell-permeable molecular probes that bind PKC domains, that incorporate new coumarin fluorophores and are readily detected by flow cytometry to show rapid kinetics of cellular uptake and efflux that promote equilibration. Additionally, I am developing a novel group of red-shifted fluorophores that can be excited between 500 and 600 nm.
Secured research funding through Pelotonia grant proposal which aims to create improved targeted triple-negative breast cancer (TNBC) therapies using SPD technology.
Employment
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The Ohio State University Post doctoral research scholar2023 - Present
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BITS Pilani Research Scholar2018 - 2023
Education
- 2018 - 2023
- 2015 - 2017
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University of Delhi B.Sc (Hons)2011 - 2014
Projects & Funding
Projects & funding information is unavailable.
Publications (16)
- Quantification of Binding of Small Molecules to Native Kinases by Flow Cytometry Reveals Divergence from Biochemical Affinities Save
- Visible Light‐Driven Difluoroalkoxylation of Imidazopyridines Using N‐Fluorobenzenesulfonimide as Fluorinating Agent Save
- Propargyl alcohol as an acrolein equivalent: synthesis of β-(3-indolyl)acroleins and β-(imidazo[1,2-a]pyridin-3-yl)acroleins Save
- Catalyst-Controlled Regiodivergent Oxidative Annulation of 2-Arylimidazo[1,2-a]pyridines with Cinnamaldehyde Derivatives for Construction of Fused N-Heterocyclic Frameworks Save
- Manganese-Catalyzed ortho-Hydroalkylation of Aryl Substituted N-Heteroaromatic Compounds with Maleimides Save
- Ball-Milling-Enabled Zn(OTf)2-Catalyzed Friedel–Crafts Hydroxyalkylation of Imidazo[1,2-a]pyridines and Indoles Save
- Selectfluor-Mediated Regioselective C-3 Alkoxylation, Amination, Sulfenylation, and Selenylation of Quinoxalin-2(1H)-ones Save
- Ruthenium(II)‐Catalyzed Annulation of 2‐Arylimidazoles with Arylglyoxals: Synthesis of 5‐Hydroxyimidazo[2,1‐a]isoquinolin‐6(5H)‐ones and Their Photophysical Studies Save
- Mechanochemical Ruthenium-Catalyzed Ortho-Alkenylation of N-Heteroaryl Arenes with Alkynes under Ball-Milling Conditions Save
- KPF6-Mediated Esterification and Amidation of Carboxylic Acids Save
- TEMPO-Mediated Synthesis of Indolyl/Imidazo[1,2-a]pyridinyl-Substituted para-Quinone Methides from Butylated Hydroxytoluene Save
- TEMPO-Mediated Cross-Dehydrogenative Coupling of Indoles and Imidazo[1,2-a]pyridines with Fluorinated Alcohols Save
- Rhodium(III)‐Catalyzed Annulation of 2‐Arylimidazo[1,2‐a]pyridines with Maleimides: Synthesis of 1H‐Benzo[e]pyrido[1′,2′:1,2]imidazo[4,5‐g]isoindole‐1,3(2H)‐Diones and their Photophysical Studies Save
- Phenyliodine(III) Diacetate-Mediated 1,2-ipso-Migration in Mannich Bases of Imidazo[1,2-a]pyridines: Preparation of N-Acetoxymethyl/Alkoxymethyl-N-arylimidazo[1,2-a]pyridine-3-amines Save
- Metal-free benzoylation of imidazoheterocycles by oxidative decarboxylation of arylglyoxylic acids Save
- A straightforward TBHP-mediated synthesis of 2-amidobenzoic acids from 2-arylindoles and their antimicrobial activity Save