YL
Ying Liu
Toronto General Research Institute-University Health Network, University of Toronto, York University
Research areas: Medicine · Endocrinology, Diabetes and Metabolism · Adipokines, Inflammation, and Metabolic Diseases · Diabetes, Cardiovascular Risks, and Lipoproteins · Autophagy in Disease and Therapy
0000-0001-7710-0809
Employment
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Toronto General Research Institute-University Health Network Research Associate2016 - Present
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University of Toronto Post-doctoral Fellow2012 - 2016
Education
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York University PhD2007 - 2012
Projects & Funding
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Uncover novel microRNAs as regulators of beta cell function Banting and Best Diabetes Centre, University of Toronto2018 - 2019
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Role of CMPF in Diabetes Development Banting and Best Diabetes Centre, University of Toronto2015 - 2016
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Discovery and characterization of zinc transporters in pancreatic beta cells Banting and Best Diabetes Centre, University of Toronto2014 - 2015
Publications (37)
- Pancreatic β cell–selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis Save
- Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study Save
- Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α Save
- CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis Save
- Elevated Medium Chain-Acylcarnitines are Associated with Gestational Diabetes, and Early Progression to Type-2 Diabetes, and Induce Pancreatic β-Cell Dysfunction Save
- Holo-Lipocalin-2 Derived Siderophores Increase Mitochondrial ROS and Impair Oxidative Phosphorylation in Rat Cardiomyocytes Save
- High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons Save
- Method for predicting the development of Type 2 Diabetes Save
- Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion Save
- Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes Save
- Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development Save
- A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells Save
- Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice Save
- Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: Roles in regulating cytosolic zinc homeostasis and insulin secretion Save
- Islet amyloid inhibitors improve glucose homeostasis in a transgenic mouse model of type 2 diabetes Save
- Metabolomic profiling in liver of adiponectin-knockout mice uncovers lysophospholipid metabolism as an important target of adiponectin action Save
- Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells Save
- Adiponectin action in skeletal muscle Save
- Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells Save
- Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome Save