NARASIMMAN PALANI

About

Narasimman Palani‒Bioinorganic Chemist.

Researcher in the field of bioinorganic chemistry, with a strong focus on manganese (Mn), iron (Fe) and copper (Cu) chemistry relevant to biocatalysis. Research aims to understand the mechanisms of O2 binding (oxidant), small molecule activation (O2, CO2, H2, CO) and reduction of dioxygen into H2O/H2O2 in nonheme Mn/Fe and Cu metal-based enzymes by designing structural and functional artificial enzyme models that mimic these naturally existing enzyme systems. A key aspect of this research involves capturing and characterizing, highly reactive high-valent Mn, Fe and Cu metal-based oxo (M=O), hydroxo (M-OH), hydroperoxo (M-OOH) and alkylperoxo (M-OOR) intermediates, which are very crucial intermediates in stereoselective biochemical oxidation process. This research contributes to the development of bio-inspired oxidation catalysts for green chemistry applications and provides a deeper understanding of structure-function relationships, offering mechanistic insights at the interface of chemistry and biology across diverse living systems. The mechanistic pathways of these enzymes are studied through using various spectroscopic, theoretical, and chemical techniques to investigate their electronic structures and reactivity behaviors.

Employment

Employment history is unavailable.

Education

• Bharathiar University PhD/Bioinorganic Chemistry
  2019 - Present
• Bharathiar University MPhil/Bioinorganic Chemistry
  2017 - 2018
• Don Bosco College: Dharmapuri, Tamil Nadu, India MSc Chemistry
  2015 - 2017
• Don Bosco College: Dharmapuri, Tamil Nadu, India BSc Chemistry
  2012 - 2015

Projects & Funding

Projects & funding information is unavailable.

Publications (4)

• Copper(ii) complexes of dipica and its derivatives as biomimetic models for phenoxazinone synthase: probing the effect of central N-cycloalkyl rings on reactivity
  New Journal of Chemistry 2026 DOI: 10.1039/D5NJ04085J
  +Save
• Iron(iii) complexes of linear 3N ligands as functional models for catechol dioxygenases: ligand modification determines the mode of coordination and extradiol cleavage activity
  Dalton Transactions 2026 DOI: 10.1039/D6DT01328G
  +Save
• Manganese(ii) complexes of tridentate 3N ligands as functional models of phenoxazinone synthase: impact of ligand steric hindrance on reactivity
  New Journal of Chemistry 2026 DOI: 10.1039/D5NJ03127C
  +Save
• Iron(III) complexes of pyrrolidine and piperidine appended tridentate 3N donor ligands as models for catechol dioxygenase enzymes
  Inorganica Chimica Acta 2022 DOI: 10.1016/j.ica.2022.120924
  +Save