Swagata Adhikari

About

I aim to understand the epigenetic reprogramming on a chromatin landscape, cross-talks between epigenetic regulators and transcription factors, post-translational modification of epigenetic regulators, which have implications in fine-tuning the transcription machinery in the context of cancer biology. I am passionately venturing the epigenetic processes behind the extracellular matrix remodeling, inflammation and drug resistance to identify the targets to reprogram the tumor microenvironment.
I have gained expertise in Biochemistry, Molecular Biology, Epigenetics, Chromatin, Cancer Biology, and Bioinformatics.
I am honoured with various publications including research articles, review and one book chapter on my field. Many successful collaborations have enriched my background.
Currently, I have defended my PhD thesis and am looking for opportunities to explore novel targets to combat cancer progression and therapy resistance.

Employment

• Saha Institute of Nuclear Physics Senior Research Fellow
  2018 - 2025

Education

• Saha Institute of Nuclear Physics Ph.D
  2018 - 2025
• University of Burdwan M.Sc.
  2014 - 2016
• University of Burdwan B.Sc
  2011 - 2014

Projects & Funding

Projects & funding information is unavailable.

Publications (18)

• UBR7 in concert with EZH2 inhibits the TGF-β signaling leading to extracellular matrix remodeling.
  Cell reports 2024 DOI: 10.1016/j.celrep.2024.114394
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• A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance.
  Oncogene 2024 DOI: 10.1038/s41388-024-03054-9
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• Protocol for evaluating extracellular matrix stiffness post-decellularization of triple-negative breast cancer cells using atomic force microscopy.
  STAR protocols 2024 DOI: 10.1016/j.xpro.2024.103460
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• Epigenetic-Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer.
  Cancer research 2023 DOI: 10.1158/0008-5472.can-22-3015
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• ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation.
  Cell death & disease 2022 DOI: 10.1038/s41419-022-05212-x
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• Human testis-specific Y-encoded protein-like protein 5 is a histone H3/H4-specific chaperone that facilitates histone deposition in vitro.
  The Journal of biological chemistry 2022 DOI: 10.1016/j.jbc.2022.102200
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• Epigenetic regulation of Fructose-1,6-bisphosphatase 1 by host transcription factor Speckled 110 kDa during hepatitis B virus infection.
  The FEBS journal 2022 DOI: 10.1111/febs.16544
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• The paradigm of drug resistance in cancer: an epigenetic perspective
  Bioscience Reports 2022 DOI: 10.1042/bsr20211812
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• Reprogramming Carbohydrate Metabolism in Cancer and Its Role in Regulating the Tumor Microenvironment.
  Sub-cellular biochemistry 2022 DOI: 10.1007/978-3-031-07634-3_1
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• TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 DOI: 10.1096/fj.202002486rr
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