Neha Khandelwal

About

I am a life science researcher with a great interest in the identification and characterization of novel therapeutic targets using the Biochemical and Chemical proteomics approaches. Currently, my work in cancer research intersects various cellular, molecular and biochemical methods to further drug development/discovery. I employ approaches to carry out high-throughput drug screening and their validations by high-resolution mass spectrometry.

Employment

• Massachusetts General Hospital Senior Research Scientist
  2026 - Present
• Massachusetts General Hospital Postdoctoral Fellow
  2021 - 2026
• Indian Institute of Science Education and Research Pune Postdoctoral Research Associate
  2020 - 2021
• Indian Institute of Science Education and Research DST-SERB National Postdoctoral Fellow
  2018 - 2020

Education

• National Chemical Laboratory CSIR PhD
  2011 - 2016

Projects & Funding

Projects & funding information is unavailable.

Publications (13)

• Systematic Targeting of Protein Complexes with Molecular COUPLrs
  Cancer Discovery 2026 DOI: 10.1158/2159-8290.CD-25-2314
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• Oxidation of retromer complex controls mitochondrial translation
  Nature 2025 DOI: 10.1038/s41586-025-08756-y
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• Systematic Targeting of Protein Complexes with Molecular COUPLrs
  2024 DOI: 10.1101/2024.07.16.603666
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• DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
  Cell 2024 DOI: 10.1016/j.cell.2024.03.027
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• DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
  2023 DOI: 10.1101/2023.10.20.563287
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• A multi-omics analysis reveals that the lysine deacetylase ABHD14B influences glucose metabolism in mammals
  Journal of Biological Chemistry 2022 DOI: 10.1016/j.jbc.2022.102128
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• Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival
  mBio 2022 DOI: 10.1128/mbio.03836-21
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• Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs
  Cell Chemical Biology 2021 DOI: 10.1016/j.chembiol.2021.01.008
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• The Lysophosphatidylserines—An Emerging Class of Signalling Lysophospholipids
  The Journal of Membrane Biology 2020 DOI: 10.1007/s00232-020-00133-2
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• Budding trends in integrated pest management using advanced micro- and nano-materials: Challenges and perspectives
  Journal of Environmental Management 2016 DOI: 10.1016/j.jenvman.2016.09.071
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