Lijun Yan

Employment

• Beijing Normal University College of Life Sciences
• University of Oxford Department of Biochemistry
• Institute of Cancer Research Chester Beatty Laboratories
• MRC Protein Phosphorylation Unit
• Cross Cancer Institute
• Harbin University of Commerce

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Astragalus polysaccharide combined with 10-hydroxycamptothecin inhibits metastasis in non-small cell lung carcinoma cell lines via the MAP4K3/mTOR signaling pathway.
  International journal of molecular medicine 2018 DOI: 10.3892/ijmm.2018.3868
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• Microbial community structures in a closed raw water distribution system biofilm as revealed by 454-pyrosequencing analysis and the effect of microbial biofilm communities on raw water quality
  Bioresource Technology 2013 DOI: 10.1016/j.biortech.2013.08.109
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• Amino acid sensing and regulation of mTORC1
  Seminars in Cell & Developmental Biology 2012 DOI: 10.1016/j.semcdb.2012.02.001
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• Signalling by amino acid nutrients.
  Biochemical Society transactions 2011 DOI: 10.1042/bst0390443
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• TPL-2-Mediated Activation of MAPK Downstream of TLR4 Signaling Is Coupled to Arginine Availability
  Virginie Mieulet, Lijun Yan, Caroline Choisy

  +8 more

  • Katherine Sully
  • Julia Procter
  • Andreas Kouroumalis
  • Steve Krywawych
  • Mario Pende
  • +3 more
  Science Signaling 2010 DOI: 10.1126/scisignal.2000934
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• Nutrient regulation of mTORC1 and cell growth.
  Cell cycle (Georgetown, Tex.) 2010 DOI: 10.4161/cc.9.13.12124
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• PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.
  Lijun Yan, Virginie Mieulet, Darren J. Burgess

  +7 more

  • Greg M. Findlay
  • Katherine Sully
  • Julia Procter
  • Jozef Goris
  • Veerle Janssens
  • +2 more
  Molecular cell 2010 DOI: 10.1016/j.molcel.2010.01.031
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• mTOR Signaling by Amino Acid Nutrients
  Structure, Function and Regulation of Tor Complexes from Yeasts to Mammals Part B 2010 DOI: 10.1016/s1874-6047(10)28004-6
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• mTORC2 is the hydrophobic motif kinase for SGK1.
  The Biochemical journal 2008 DOI: 10.1042/bj20082202
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• A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.
  The Biochemical journal 2007 DOI: 10.1042/BJ20061881
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• Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.
  The Journal of biological chemistry 2006 DOI: 10.1074/jbc.c600028200
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• Knockout of ERK5 causes multiple defects in placental and embryonic development.
  BMC developmental biology 2003 DOI: 10.1186/1471-213X-3-11
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• Effect of vanadyl ions on calcineurin and its A subunit.
  Biological chemistry 2000 DOI: 10.1515/bc.2000.040
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• High activity of the calcineurin A subunit with a V314 deletion.
  Biological chemistry 1999 DOI: 10.1515/bc.1999.163
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