PK
Pawan Kumar
Kurukshetra University
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · DNA and Nucleic Acid Chemistry · Advanced biosensing and bioanalysis techniques · RNA and protein synthesis mechanisms
0000-0001-7936-4613
Employment
Employment history is unavailable.
Education
- 2006 - 2010
Projects & Funding
Projects & funding information is unavailable.
Publications (58)
- Conformation matters: siRNAs with antisense strands with 5′-(E)-vinyl-phosphonate-α-l-LNA elicit stronger RNAi-mediated gene silencing than those with 5′-(E)-vinyl-phosphonate-LNA Save
- Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing Save
- siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs Save
- DNA Analogues Modified at the Nonlinking Positions of Phosphorus Save
- Base‐Pairing Properties of Double‐Headed Nucleotides Save
- Synthesis and Biophysical Characterization of RNAs Containing 2′-Fluorinated Northern Methanocarbacyclic Nucleotides Save
- 5′-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger Save
- Synthesis, Affinity for Complementary RNA and DNA, and Enzymatic Stability of Triazole-Linked Locked Nucleic Acids (t-LNAs) Save
- Novel PNA hybrid sequences as recognition units in SNARE protein mimicking peptides Save
- Condensing the information in DNA with double-headed nucleotides Save
- Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA Save
- Synthesis, hybridization and fluorescence properties of a 2 '-C-pyrene-triazole modified arabino-uridine nucleotide Save
- Double-Headed Nucleotides: Building Blocks for New Nucleic Acid Architectures Save
- Incorporation of sulfonamido-substituted benzothiazole moiety at C5-position of deoxyuridine through an alkynyl linker: A Sonogashira approach Save
- Role of the transmembrane domain in SNARE protein mediated membrane fusion: peptide nucleic acid/peptide model systems Save
- Three new double-headed nucleotides with additional nucleobases connected to C-5 of pyrimidines; synthesis, duplex and triplex studies Save
- Allele-Selective Inhibition of Mutant Huntingtin with 2-Thio- and C5-Triazolylphenyl-Deoxythymidine-Modified Antisense Oligonucleotides Save
- Double-headed nucleotides introducing thymine nucleobases in the major groove of nucleic acid duplexes Save
- Increasing the Stability of DNA:RNA Duplexes by Introducing Stacking Phenyl-Substituted Pyrazole, Furan, and Triazole Moieties in the Major Groove Save
- SNARE protein analog-mediated membrane fusion Save