About
I obtained my graduate (PhD) degree from the Centre for Cellular & Molecular Biology, Hyderabad, India in the broad area of microbial osmoadaptation in 2001. From 2000 to 2002 I worked as a post-doctoral fellow at the University of Geneva, Switzerland studying the mechanisms of protein folding in the bacterial periplasm. From 2002 to 2007 I worked as a research associate/project investigator at CDFD and joined its scientific staff in 2007. Research in my laboratory is broadly concerned with the study of integral membrane proteins of E. coli involved in adaptive solute transport. Regulatory mechanisms concerned with the above are also being studied.
Employment
-
Centre for DNA Fingerprinting and Diagnostics Group Leader2007 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (17)
- Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations Save
- Topological analyses of the L-lysine exporter LysO reveal a critical role for a conserved pair of intramembrane solvent-exposed acidic residues Save
- The Topology of the l-Arginine Exporter ArgO Conforms to an Nin-Cout Configuration in Escherichia coli: Requirement for the Cytoplasmic N-Terminal Domain, Functional Helical Interactions, and an Aspartate Pair for ArgO Function Save
- Growth inhibition by external potassium of Escherichia coli lacking PtsN (EIIANtr) is caused by potassium limitation mediated by YcgO Save
- Distinct paths for basic acid export in Escherichia coli:YbjE(LysO) meidates export of L-lysine Save
- Inactivation of the Bacterial RNA Polymerase Due to Acquisition of Secondary Structure by the ω Subunit Save
- DNA Clasping by Mycobacterial HU: The C-Terminal Region of HupB Mediates Increased Specificity of DNA Binding Save
- Identifying N60D mutation in ω subunit of Escherichia coli RNA polymerase by bottom-up proteomic approach Save
- Facilitated Oligomerization of Mycobacterial GroEL: Evidence for Phosphorylation-Mediated Oligomerization Save
- Th1-type immune response to infection by pYV-cured phoP-phoQ null mutant of Yersinia pseudotuberculosis is defective in mouse model Save