SRINIVASAN, RAMANUJAM
National Institute of Science Education and Research, Indian Institute of Technology, Indian Institute of Science, Madurai Kamaraj University, RCE in Mechanobiology National University of Singapore
0000-0001-8071-6110
About
Research Interest
Bacterial Pathogenesis, Cytoskeletal Dynamics and Function
• Cell division and Spatial organization in Bacteria - Bacterial cytoskeleton dynamics, Cytokinetic ring assembly, Regulation of cell division control and anti-bacterials targeting bacterial cytoskeleton.
• Bacterial Metabolism & Biofilms - Molecular pathways by which Bacterial proteases regulate lipid metabolism & biofilm formation.
• Bacterial Pathogenesis - Molecular Mechanisms of Bacterial effectors that target and affect Eukaryotic Cytoskeleton.
• Synthetic Biology - Synthetic Protein Polymers: architecture/ landscapes & Evolution of synthetic cytomotive proteins for use in biological & artificial cell systems.
Employment
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National Institute of Science Education and Research Associate Professor2022 - Present
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National Institute of Science Education and Research READER-F2014 - 2022
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Indian Institute of Technology Assistant Professor2014 - 2014
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RCE in Mechanobiology National University of Singapore RESEARCH FELLOW2010 - 2014
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Temasek Life Sciences Laboratory Ltd RESEARCH FELLOW2006 - 2009
Education
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Indian Institute of Science Integrated PhD1997 - 2006
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Madurai Kamaraj University Bachelor of Science1994 - 1997
Projects & Funding
Projects & funding information is unavailable.
Publications (61)
- Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723 Save
- Distinct filament morphology and membrane tethering features of the dual FtsZ paralogs in Odinarchaeota Save
- Mechanistic Insights into Z-Ring Formation and Stability Save
- Mutational analysis of the F plasmid partitioning protein ParA reveals residues required for oligomerization and plasmid maintenance Save
- Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance Save
- A mechanism of salt bridge–mediated resistance to FtsZ inhibitor PC190723 revealed by a cell-based screen Save
- Mechanistic insights into GTP-dependence and kinetic polarity of FtsZ filament assembly Save
- Filament organization of the bacterial actin MreB is dependent on the nucleotide state Save
- A salt bridge-mediated resistance mechanism to FtsZ inhibitor PC190723 revealed by a cell-based screen Save
- A role for the last C-terminal helix of the F plasmid segregating protein SopA in nucleoid binding and plasmid maintenance. Save