Rajesh Manda
National Institute of Technology Warangal, Indian Institute of Chemical Technology, University of Nebraska Medical Center, Purdue University, Panacea Biotec Ltd
0000-0001-8106-6527
About
I am currently working as an Assistant Professor at NIT Warangal. My research mainly focused on the synthesis of bioactive molecules through various methodologies. I also worked as a Postdoctoral Research Associate in the Eppley Cancer Research at the University of Nebraska Medical Center (UNMC), Omaha. My research mainly focuses on synthesizing Regulated induced proximity targeting chimeras (RIPTACs) and Proteolysis Targeting Chimeras (PROTACs). I also worked as a PDRA in the Department of Chemistry at Purdue University, West Lafayette, USA. My research at Purdue focused on synthesizing selective G Protein Coupled Receptor (GPCR) kinase inhibitors and Natural Product Synthesis. Despite of current work, I have a broad background in synthetic organic chemistry and medicinal chemistry with specific training and expertise in the synthesis of small to complex molecular architectures in short path. As a Project Researcher, I have developed the new synthetic route for chiral nicotine's synthesis cost-effectively in a multi-gram scale. During my Ph.D., I successfully disclosed the novel reactivities of alkynes for the synthesis of medicinally impartment functionalized heterocyclic complexes and produced multiple publications along with various fascaplysin derivatives and other industrial collaborated projects. Outside of the lab, I enjoy watching movies, cooking food, drinking good beer, and spending time with family.
Employment
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National Institute of Technology Warangal Assistant Professor2024 - Present
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Indian Institute of Chemical Technology Project Researcher2020 - 2021
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Panacea Biotec Ltd Executive Research Chemist2012 - 2014
Education
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University of Nebraska Medical Center Postdoctoral Research Associate2024 - 2024
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Purdue University Postdoctoral Fellow2021 - 2024
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Indian Institute of Chemical Technology2017 - 2020
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CSIR-CDRI Ph.D2014 - 2017
Projects & Funding
Projects & funding information is unavailable.
Publications (28)
- Application of Hydroxy Propargylic Alcohols in Organic Synthesis Save
- Potent and selective G protein-coupled receptor kinase 5 inhibitors: Design, synthesis, evaluation, and X-ray structural studies Save
- Microwave-assisted, Pd-catalyzed one-pot synthesis of δ-carbolines through demethylative amine arylation Save
- Modular Synthesis of Triaroyl Cyclopropanes via a Formal Cyclotrimerization of Phenacyl Bromides and Their Transformation into Diazabicycles Save
- Visible-Light-Induced Insertion of Siloxycarbene into Amide N–H Bonds: Synthesis of Carbinolamides from Acylsilanes and Amides Save
- Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes. Save
- Recent Progress in Arylmetalative Cyclization/Annulation of Functionalized Alkynes with Organoboranes Save
- Acylsilane Directed Rh-Catalyzed Arene C–H Alkylation with Maleimides and Visible-Light-Induced Siloxycarbene-Amide Cyclization: [3 + 2] Carbo-Annulation in Ru Catalysis Save
- Synthesis of bridgehead-azacycles via dual C–N/C–C annulation of α-amino acids, aminals and maleimides Save
- Activator free diastereoselective 1,3-dipolar cycloaddition: a quick access to coumarin based spiro multi heterocyclic adducts Save