Israful Hoque

About

Development of new generation Anti-Viral drugs for the treatment of Covid-19 disease.
PROTACs against metabolic diseases, Design, Synthesis and evaluation of BacPROTACs mediate targeted protein degradation in bacteria to mitigate the AntiMicrobial Registant (AMR).

Employment

• North Bengal University SERB JRF FELLOW
  2020 - 2021
• TCG Lifesciences Ltd Senior Research Chemist
  2016 - 2020

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (6)

• Targeted Screening and Rational Optimization of Bazedoxifene Analogues as Pan-Variant SARS-CoV-2 Entry Inhibitors with Improved Pharmacokinetics
  European Journal of Medicinal Chemistry 2025 DOI: 10.1016/j.ejmech.2025.118462
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• Strategic Design and Optimization of Umifenovir Analogues: Balancing Antiviral Efficacy and hERG Toxicity against SARS-CoV-2
  Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c03093
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• INDOLE-BASED SMALL MOLECULE ANTIVIRALS AGAINST SARS-COV-2
  World patent, Indian patent; WO2025203062A1·2025-10-02 2025
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• Rational design and discovery of potent PROTAC degraders of ASK1: a targeted therapy in MASH
  RSC Medicinal Chemistry 2025 DOI: 10.1039/d5md00252d
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• PROTACS FOR ASK1 PROTEIN DEGRADATION: PREPARATION AND USE THEREOF
  WO2024236595A1, IN2024050526W 2024
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• A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF
  CN118451062A;EP4452952A1;WO2023119320A1, IN202111061087A 2023
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