Oishika Chatterjee

About

I am a molecular and structural biologist specializing in G-quadruplex biology, transcriptional regulation, and nucleic acid–ligand interactions in cancer. I completed my Ph.D. in Biochemistry from Bose Institute, Kolkata (DST, Govt. of India) in affiliation with the University of Calcutta, and hold an Integrated BSc–MSc in Biotechnology (First Class Honours) from St. Xavier's College, Kolkata.

My research focuses on the structural and functional roles of G-quadruplex DNA in triple-negative breast cancer (TNBC), combining molecular biology, biophysical characterization (ITC, CD spectroscopy, NMR), and computational modeling to explore regulatory mechanisms and therapeutic targeting strategies.

I have authored publications in Cell Calcium, Drug Discovery Today, and Advances in Colloid and Interface Science. I am broadly interested in mechanistic studies of nucleic acid structure–function relationships and their translational potential in cancer therapeutics.

Employment

• Bose Institute Senior Research Fellow
  2020 - 2026

Education

• University of Calcutta PhD.
  2022 - 2026
• St Xavier's University MSc.
  2014 - 2019

Projects & Funding

Projects & funding information is unavailable.

Publications (3)

• Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer
  Cell Calcium 2024 DOI: 10.1016/j.ceca.2024.102944
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• Targeting Ca2+ signaling: A new arsenal against cancer
  Drug Discovery Today 2022 DOI: 10.1016/j.drudis.2021.11.012
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• Curcumin arrests G-quadruplex in the nuclear hyper-sensitive III1 element of c-MYC oncogene leading to apoptosis in metastatic breast cancer cells
  Journal of Biomolecular Structure and Dynamics 2021 DOI: 10.1080/07391102.2021.1940284
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