Abhishek Saha

About

Abhishek Saha was born in West Bengal, India in 1991. Abhishek received his M.Sc. in organic chemistry in 2014 with a distinguished silver medal from the University of North Bengal, India. Abhishek obtained his Ph.D. under Prof. Debasis Manna in 2020 from the Indian Institute of Technology Guwahati (IIT-G), India. In the same year, Abhishek joined as a postdoctoral researcher in Prof. Ashraf Brik’s laboratory, the Schulich Faculty of Chemistry at the Technion-Israel Institute of Technology, Israel. Where, his research was focused on modulating the activities of biologically relevant proteins and enzymes for developing new drug molecules for cancer and other diseases, as well as developing new cell-penetrating peptides for live cell delivery of synthetic proteins. In 2024, Abhishek joined the department of chemistry at Birla Institute of Technology and Science Pilani at the Hyderabad campus as an assistant professor. His independent research lab is focused on exploring and understanding THE ART OF INTRACELLULAR CHEMICAL DELIVERY.

https://www.bits-pilani.ac.in/hyderabad/dr-abhishek-saha/

Employment

• Birla Institute of Technology and Science - Hyderabad Campus Assistant Professor
  2024 - Present

Education

• Technion – Israel Institute of Technology Postdoctoral Research fellow
  2020 - 2024
• Indian Institute of Technology Guwahati Ph.D.
  2015 - 2020

Projects & Funding

Projects & funding information is unavailable.

Publications (18)

• Strategies to improve intracellular delivery of arginine-rich cell-penetrating peptides
  Journal of Materials Chemistry B 2026 DOI: 10.1039/D5TB02935J
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• Amphipathic Cell-Penetrating Peptide-based Molecular Transporters: A Balanced Approach for Membrane Penetration
  European Journal of Medicinal Chemistry 2026 DOI: 10.1016/j.ejmech.2026.119322
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• Suspension Bead Loading (SBL): An Economical Protein Delivery Platform to Study URM1’s Behavior in Live Cells
  Angewandte Chemie International Edition 2024 DOI: 10.1002/anie.202410135
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• Exocyclic and Linker Editing of Lys63‐linked Ubiquitin Chains Modulators Specifically Inhibits Non‐homologous End‐joining Repair
  Angewandte Chemie International Edition 2024 DOI: 10.1002/anie.202409012
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• Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes
  Accounts of Chemical Research 2023 DOI: 10.1021/acs.accounts.3c00178
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• Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins
  Angewandte Chemie International Edition 2022 DOI: 10.1002/anie.202207551
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• Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen
  Angewandte Chemie 2022 DOI: 10.1002/ange.202207551
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• Selective macrocyclic peptide modulators of Lys63-linked ubiquitin chains disrupt DNA damage repair
  Nature Communications 2022 DOI: 10.1038/s41467-022-33808-6
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• Chloride Ion Transport by PITENINs across the Phospholipid Bilayers of Vesicles and Cells
  ACS Applied Bio Materials 2020 DOI: 10.1021/acsabm.9b00985
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• Sunlight-Mediated Thiol–Ene/Yne Click Reaction: Synthesis and DNA Transfection Efficiency of New Cationic Lipids
  ACS Omega 2020 DOI: 10.1021/acsomega.9b03413
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