0000-0001-8557-9450 About
Dr. Santosh Kumar Rath is an Assistant Professor in Faculty of Pharmacy, DIT University since 2nd March 2022. Dr. Rath is a medicinal and natural product chemist having over 8 years of experience in research, academia and industry. Dr Rath received his PhD in 2022 from AcSIR under the supervision of Dr Sanjib Das, Principal Scientist, Materials Chemistry Department at CSIR-Institute of Minerals and Materials Technology (CSIR-IMMT), Bhubaneswar, India. Formerly, he worked as an Associate Professor and Research Head at the department of Pharmaceutical Chemistry, Danteswari College of Pharmacy, Jagdalpur, Chhattisgarh. He also worked as Research Associate (CSIR-RA) in School of Chemistry & Biochemistry at Thapar Institute of Engineering & Technology, Patiala, India. He got awarded Senior Research Fellowship (ICMR-SRF) from ICMR, New Delhi India and did research work at CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu, India. Dr. Santosh has published more than 17 research papers in reputed journals and filed 1 Indian patent.
Dr. Rath is well trained in organic synthesis and characterization techniques, including HPLC and 2D-NMR techniques. Dr. Rath is working on isolation & characterization of bioactive molecules from natural sources, performs structural modification on major bioactive isolates and their SAR studies. His research areas involve multistep synthesis of biologically active synthetic and/or natural product based hybrid scaffolds for lead identification in special target to neurological disease, cancer, HIV, Covid-19 and infectious diseases. His research is mainly focussed on the synthesis of novel P-gp and bacterial efflux pump inhibitors, besides synthetic modifications of the bioactive natural products for better activity/less toxicity profiles.
Research Interest:
Medicinal Chemistry and Organic Synthesis
Natural Product Chemistry
Synthetic Methodology
Synthesis of drug conjugates and lipid based multifunctional nanoformulations
Employment
Employment history is unavailable.
Education
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Publications (32)
- Quantitative Estimation and Biosynthetic Pathways Study of Artemisinin in Artemisia tournefortiana: An Alternative Source for Artemisinin Save
- Structural Characterization, In Vitro Antidiabetic Activity, and Molecular Docking Studies of Isolated Compounds From Allamanda cathartica Save
- Exploring herbal synergies in the management of rheumatoid arthritis: a multifaceted approach to inflammation and joint health Save
- A Glimpse for the subsistence from pandemic SARS-CoV-2 infection Save
- Structural characterization, in-silico studies, and antifungal activity of 5-methylmellein isolated from endophytic Alternaria burnsii Save
- Computational and in-vitro Investigation of Phytochemicals from Allamanda cathartica as a Potential Candidate for the Treatment of Type 2 Diabetes mellitus Save
- Purification of ursolic acid and β-sitosterol from endophytic Alternaria alternata for their alpha-amylase inhibitory activity Save
- Isolation, chemical characterization, antimicrobial activity, and molecular docking studies of 2,6-dimethoxy benzoquinone isolated from medicinal plant Flacourtia jangomas Save
- Nanomaterials and Neurological Disorders Management Save
- Harnessing the action mechanisms of microbial endophytes for enhancing plant performance and stress tolerance: current understanding and future perspectives Save