Carlos Talavera-López

Employment

• GlaxoSmithKline Director
  2025 - Present
• Julius-Maximilians-Universität Würzburg Medizinische Fakultät Junior Professor
  2023 - 2025
• Helmholtz Zentrum München Group Leader
  2022 - 2023
• Helmholtz Zentrum München Senior Postdoctoral Fellow
  2021 - 2022
• European Bioinformatics Institute Postdoctoral Fellow
  2018 - 2021
• Wellcome Sanger Institute Staff Scientist
  2018 - 2021
• Francis Crick Institute Postdoctoral Fellow
  2016 - 2018
• Karolinska Institutet Ph.D Student
  2012 - 2016
• Science for Life Laboratory Bioinformatician
  2011 - 2012
• Ministerio de Salud de Nicaragua Researcher
  2011 - 2011
• Universidad Centroamericana Researcher
  2008 - 2010

Education

• Karolinska Institutet Ph.D
  2012 - 2016
• Universidad Nacional Autónoma de Nicaragua-León Diagnostic Medicine
  2004 - 2010

Projects & Funding

Projects & funding information is unavailable.

Publications (36)

• Biologically informed deep learning to infer gene program activity in single cells
  2022 DOI: 10.1101/2022.02.05.479217
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• A Python library for probabilistic analysis of single-cell omics data
  Nature Biotechnology 2022 DOI: 10.1038/S41587-021-01206-W
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• Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans
  Cell Reports 2021 DOI: 10.1016/j.celrep.2021.109174
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• Experimental microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid diversification of genome sequence and structure
  bioRxiv 2021 DOI: 10.1101/2021.10.24.465605
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• Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi
  Frontiers in Cellular and Infection Microbiology 2021 DOI: 10.3389/fcimb.2021.614665
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• Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
  Christoph Muus, Malte D. Luecken, Gökçen Eraslan

  +97 more

  • Lisa Sikkema
  • Avinash Waghray
  • Graham Heimberg
  • Yoshihiko Kobayashi
  • Eeshit Dhaval Vaishnav
  • +92 more
  Nature Medicine 2021 DOI: 10.1038/s41591-020-01227-z
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• User-friendly, scalable tools and workflows for single-cell RNA-seq analysis
  Pablo A Moreno, Ni Huang, Jonathan R. Manning +20 more
  Nature Methods 2021 DOI: 10.1038/s41592-021-01102-w
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• Cells of the adult human heart
  Nature 2020
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• Cells and gene expression programs in the adult human heart
  2020 DOI: 10.1101/2020.04.03.024075
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• Activation of a neural stem cell transcriptional program in parenchymal astrocytes
  eLife 2020 DOI: 10.7554/ELIFE.59733
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• Activation of a neural stem cell transcriptional program in parenchymal astrocytes
  bioRxiv 2020 DOI: 10.1101/2020.07.20.211409
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• Cells of the adult human heart
  Nature 2020 DOI: 10.1038/s41586-020-2797-4
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• Divergent Clonal Differentiation Trajectories Establish CD8 + Memory T Cell Heterogeneity during Acute Viral Infections in Humans
  SSRN 2020 DOI: 10.2139/ssrn.3606766
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• Expression Atlas update: From tissues to single cells
  Irene Papatheodorou, Pablo A Moreno, Jonathan R. Manning

  +22 more

  • Alfonso Muñoz-Pomer Fuentes
  • Nancy George
  • Silvie Korena Fexova
  • Nuno A. Fonseca
  • Anja Füllgrabe
  • +17 more
  Nucleic Acids Research 2020 DOI: 10.1093/nar/gkz947
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• SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
  Nature Medicine 2020 DOI: 10.1038/s41591-020-0868-6
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• User-friendly, scalable tools and workflows for single-cell analysis
  bioRxiv 2020 DOI: 10.1101/2020.04.08.032698
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• A cellular census of human lungs identifies novel cell states in health and in asthma
  Nature Medicine 2019 DOI: 10.1038/s41591-019-0468-5
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• Clonally distinct differentiation trajectories shape CD8+ memory T cell heterogeneity after acute viral infections in humans
  bioRxiv 2019 DOI: 10.1101/832899
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• Comparison of whole blood and spleen transcriptional signatures over the course of an experimental malaria infection
  Scientific Reports 2019 DOI: 10.1038/s41598-019-52388-y
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• Correction to: Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type i Interferon signaling (BMC Res Notes (2018) 11 (913) DOI: 10.1186/s13104-018-4020-3)
  BMC Research Notes 2019 DOI: 10.1186/s13104-019-4069-7
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