CT
Charmy Twala
University of South Africa, University of the People, University of the Witwatersrand, University of the Witwatersrand Johannesburg
Research areas: Chemistry · Organic Chemistry · Synthesis and biological activity · Synthesis and Characterization of Heterocyclic Compounds · Computational Drug Discovery Methods
0000-0001-8731-7032
Employment
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University of the People Instructor2022 - 2022
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University of South Africa Lecturer2019 - Present
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University of the Witwatersrand Johannesburg Academic Intern2018 - 2019
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University of the Witwatersrand Teaching Assistant2016 - 2017
Education
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University of the Witwatersrand Master of Science (MSc) - Bioinformatics2016 - 2017
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University of the Witwatersrand HDIP in Computer Science2015 - 2015
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University of the Witwatersrand Bachelor of Science (BSc) - Molecular and Cell Biology2011 - 2014
Projects & Funding
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SCARCE SKILLS MASTERS AND DOCTORAL SCHOLARSHIP FOR 2016 - 2017 National Research Foundation (NRF)2016 - 2017
Publications (15)
- Computational Chemistry Approaches on Hepatitis Drug Discovery Save
- Computational Evaluation of Novel PARP-1 Inhibitors for Breast Cancer: Docking, Molecular Dynamics, MM/GBSA, DFT and ADMET Calculations Save
- Computational Chemistry Advances in the Development of PARP1 Inhibitors for Breast Cancer Therapy Save
- Exploring the binding energies of new pyrazoline derivatives to DNA/BSA: antifungal, antioxidant, MD simulations and TD-DFT studies Save
- Medicinal Plant‐Derived Caffeoylquinic Acids as Inhibitors of Rift Valley Fever Virus: A Computational Study Save
- Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassipes Hook tubers Save
- Ezetimibe Anticancer Activity via the p53/Mdm2 Pathway Save
- Ezetimibe anticancer activity via the p53/Mdm2 pathway: Implications for RBBP6 Save
- Novel dihydrobenzofuran derivatives: design, synthesis, cytotoxic activity, apoptosis, molecular modelling and DNA binding studies Save
- Pd-catalyzed synthesis, characterization, and biological evaluations of pyrazole derivatives: DFT, molecular modelling and antioxidant studies Save
- Pd-catalyzed synthesis, characterization, and biological evaluations of pyrazole derivatives: DFT, molecular modelling and antioxidant studies Save
- Modified ezetimibe drug for cancer treatment Save
- 1,3,4-oxadiazole derivatives: synthesis, characterization, antifungal activity, DNA binding investigations, TD-DFT calculations, and molecular modelling Save
- Synthesis, spectral characterization of pyrazole derived Schiff base analogs: molecular dynamic simulation, antibacterial and DNA binding studies Save
- Drugs targeting the Retinoblastoma Binding Protein 6 (RBBP6): "the collision of computers and biochemistry" Save