Hifzur R Siddique
Aligarh Muslim University, University of Southern California, CSIR-Indian Institute of Toxicology Research, University of Minnesota
About
Resistance to therapy severely limits the effectiveness of chemotherapy drugs in treating cancer. For Advanced Cancer, the progression of tumors to the state of chemoresistance, the paucity of knowledge about the mechanism of chemoresistance and lack of therapeutic molecule/s are major stumbling blocks in the management and treatment of disease in cancer patients. Primary or acquired drug resistance remains a fundamental cause of therapeutic failure in cancer therapy. Ever since I have started my research life, I have been trying to understand how different cells, gene, proteins, might contribute to initiation, progression, and Chemoresistance of cancer. Unraveling drug resistance mechanisms and discovery of new therapeutic molecule/s are not only facilitating rational treatment strategies to overcome existing limitations in therapeutic efficacy but will enhance biomarker discovery and the development of companion diagnostics.
Employment
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Aligarh Muslim University Senior Assistant Professor2018 - Present
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Aligarh Muslim University Assistant Professor2017 - 2018
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University of Southern California Research Associate2013 - 2016
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University of Minnesota Senior Research Associate2012 - 2013
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University of Minnesota Hormel Fellow2010 - 2012
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University of Wisconsin Madison Research Associate2008 - 2010
Education
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CSIR-Indian Institute of Toxicology Research Ph.D.2003 - 2008
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Aligarh Muslim University M.Sc.1998 - 2000
Projects & Funding
Projects & funding information is unavailable.
Publications (107)
- Generative artificial intelligence and large language models in smart healthcare applications: Current status and future perspectives Save
- Liver-Associated Disorders and Gut-Friendly Food Save
- An update understanding of stemness and chemoresistance of prostate cancer Save
- Types, stability, biocompatibility, and toxicity of protein-based nanocomposites Save
- Chemotherapeutic potential of lupeol against cancer in pre-clinical model: A systematic review and meta-analysis Save
- Apigenin enhances sorafenib anti-tumour efficacy in hepatocellular carcinoma Save
- Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects Save
- Coupling effect of micro-textured tools and cooling conditions on the turning performance of aluminum alloy 6061 Save
- Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages Save
- Research and Patents Status of Selected Phytochemicals Against Cancer: How Close and How Far? Save