AG
Alfredo Guerra
University of Michigan Medical School, University of Michigan, Indiana University, Universidad de Costa Rica, Johns Hopkins University Bloomberg School of Public Health
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Toxoplasma gondii Research Studies · Malaria Research and Control · Protein Structure and Dynamics
0000-0001-8764-8413
Employment
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University of Michigan Medical School Research Investigator2019 - Present
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University of Michigan Research Fellow2017 - 2019
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Johns Hopkins University Bloomberg School of Public Health Postdoctoral Fellow2012 - 2016
Education
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Indiana University Ph D? - 2012
- ? - 2007
Projects & Funding
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The POA-RpsA interaction in trans-translation inhibition in M. tuberculosis National Institute of Allergy and Infectious Diseases2014 - 2017
Publications (17)
- Toxoplasma GRA8 engages the host ESCRT accessory protein ALG-2 and is necessary for parasite metabolic integrity Save
- The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii Save
- mSphere of Influence: Ushering in the CRISPR Revolution to Toxoplasma Biology Save
- Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress Save
- Structural basis of Toxoplasma gondii Perforin-Like Protein 1 membrane interaction and activity during egress Save
- Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability Save
- A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species Save
- Crystal structure of lipoate-bound lipoate ligase 1, LipL1, from Plasmodium falciparum Save
- Structural features of apicomplexan pore-forming proteins and their roles in parasite cell traversal and egress Save
- Backbone and sterospecific methyl side chain resonance assignments of the homodimeric zinc sensor AdcR (32 kDa) in the apo- And Zn(II)-bound states Save
- Allosteric inhibition of a zinc-sensing transcriptional repressor: Insights into the arsenic repressor (ArsR) family Save
- Energetics of zinc-mediated interactions in the allosteric pathways of metal sensor proteins Save
- Metal-Regulated Gene Expression Save
- Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods Save
- Metal site occupancy and allosteric switching in bacterial metal sensor proteins Save
- Crystal structure of the zinc-dependent MarR family transcriptional regulator AdcR in the Zn(II)-bound state Save
- The metalloregulatory zinc site in streptococcus pneumoniae AdcR, a Zinc-activated MarR family repressor Save